1 Product identity
Ingredient risk
Contains a high-risk ingredient
Take Heart II Without Hormones
BrandAllergy Research Group→Other Combinations Powder 89 ingredients 1 high-risk 6 caution DSLD #54477Net contents: 300 Gram(s)
Target: Adults and Children 4 years and above
DSLD entry: 2015-12-23
2 Ingredients (89)
IngredientGroupSafety
CaloriesCalories—
Calories from FatCalories—
Total FatFat (unspecified)—
Saturated FatSaturated fat—
CholesterolCholesterol—
Total CarbohydratesCarbohydrate—
Dietary FiberFiber (unspecified)—
SugarSugar—
ProteinProtein (unspecified)—
Alpha-CaroteneAlpha-carotene—
Para-Aminobenzoic AcidPABA—
Soy Lecithinlecithin—
L-AlanineAlanine—
L-Aspartic AcidAspartic Acid—
Alpha-Glucan OligosaccharideAlpha Glucans—
L-HistidineHistidine—
L-IsoleucineIsoleucine—
L-OrnithineOrnithine—
L-SerineSerine—
L-ThreonineTHREONINE—
L-ValineValine—
N-Acetyl-L-CysteineN-Acetyl Cysteine—
PancreatinBlend (non-nutrient/non-botanical)—
Grape skin extractGrape —
GarlicGarlic—
LycopeneLycopene—
Eicosapentaenoic AcidEPA (Eicosapentaenoic Acid)—
Docosahexaenoic AcidDHA (Docosahexaenoic Acid)—
Gamma-Linolenic AcidGamma Linolenic Acid—
Linolenic AcidLinolenic acid (unspecified)—
Oleic AcidOleic Acid—
Palmitic AcidPalmitic Acid—
Stearic AcidStearic Acid—
Lipoic AcidAlpha Lipoic Acid—
Oat BranOat Fiber—
Honey powderHoney—
Rice BranRice Bran—
PsylliumPsyllium (unspecified)—
Apple FiberApple fiber—
SteviaStevia—
FlavoringFlavor—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Vitamin K — Limited Evidence
⚠ Critical interaction with warfarin
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Vanadium — Limited Evidence
⚠ GI toxicity: nausea, vomiting, diarrhea
⚠ Green tongue
Coenzyme Q10 — Limited Evidence
⚠ May reduce warfarin efficacy
⚠ Mild GI effects
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Choline — Generally Safe
⚠ Fishy odor at high doses
L-Arginine — Limited Evidence
⚠ Hypotension
⚠ May worsen herpes outbreaks
L-Carnitine — Generally Safe
⚠ Fishy body odor
⚠ TMAO concern
L-Glutamine — Conditionally Safe
⚠ Hepatic encephalopathy risk
⚠ May elevate ammonia
Glycine — Generally Safe
⚠ Well tolerated
L-Leucine — Limited Evidence
⚠ May worsen pellagra
⚠ High doses may impair glucose metabolism
L-Lysine — Limited Evidence
⚠ GI discomfort at high doses
⚠ May increase calcium absorption
L-Methionine — Limited Evidence
⚠ Raises homocysteine levels
⚠ May promote tumor growth
L-Phenylalanine — Limited Evidence
⚠ Dangerous in PKU
⚠ May raise blood pressure
L-Proline — Limited Evidence
⚠ Well tolerated
⚠ Important for collagen synthesis
Taurine — Generally Safe
⚠ May lower blood pressure
L-Tyrosine — Limited Evidence
⚠ May worsen hyperthyroidism
⚠ Migraine trigger in some
Glutathione — Generally Safe
⚠ Limited oral bioavailability data
⚠ May affect zinc levels
Papain — Conditionally Safe
⚠ Allergic reactions
⚠ Increased bleeding risk
Bromelain — Conditionally Safe
⚠ Increased bleeding risk
⚠ GI upset
Hawthorn — Conditionally Safe
⚠ Additive with digoxin
⚠ Hypotension
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Methylsulfonylmethane — Generally Safe
⚠ GI effects
⚠ Headache
Flaxseed Oil — Generally Safe
⚠ High ALA but poor conversion to EPA/DHA
⚠ May increase bleeding risk
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID54477
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2015-12-23
6 More from Allergy Research Group
View Allergy Research Group Safety Scorecard → 76 products
Acetyl-Glutathione 300 mgAdrenal CortexAller-Aid Formula IIAmmonium Chloride BufferedBrain Beef Natural GlandularBrainWave Plus7 Cite this page
Vancouver
Pkhakadze G. Take Heart II Without Hormones — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 17]. Available from: https://supplement.ge/products/take-heart-ii-without-hormones-54477/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG