SAFE

Vitamin D

Cholecalciferol
Likely Safe V1 Verified Vitamins
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PubMed Studies
5,577
PubChem CID
⚖️ Regulatory Status
⚠️
EU — Restricted
EFSA established Tolerable Upper Intake Level of 100mcg (4,000 IU)/day for adults. Daily doses >100mcg require medical supervision.
👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNot established
PregnancyLikely safeNot established
ElderlyLikely safeNot established
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, or taking medications. Do not exceed the recommended daily dose.

💊 Drug Interactions (5)
🟡 Thiazide diuretics
Moderate
Diuretics
Management: Monitor serum calcium regularly.
🟡 Cyclosporine / Tacrolimus
Moderate
Immunosuppressants
Management: Monitor Vitamin D. Supplementation often required.
⚪ Atorvastatin
Minor
Statins
Management: Monitor Vitamin D levels in statin users.
⚪ Metformin
Minor
Antidiabetics
Management: Monitor Vitamin D status in metformin users.
⚪ SSRIs
Minor
Antidepressants
Management: Safe and potentially beneficial.
🏷️ Other Names
Cholecalciferol
Updated: 2026-04-11
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