✓ No active regulatory warningsFDA MedWatch, EMA EudraVigilance, WHO VigiBase, WADA Prohibited List · 2026-05-29
Updated: 2026-05-29 · v2.0 · Prof. G. Pkhakadze, MD, MPH, PhDCiteEditorial
📰Read the full Boron evidence review on GMJ News →Complete clinical article, references and updates on news.gmj.ge. This page is the structured safety summary.
2
Conditional
Boron
Boron glycinate
Conditionally SafeLimitedTrace Minerals
RDA
Typical 1–3 mg
Target
N/A
Upper limit
20 mg
Products
1,039
Dosage by population group — reference
🔗 Best with: Calcium, Vitamin D, Magnesium, Vitamin K2 (MK-7)✅ USP Verified, NSF Contents Certified, Clean Label Project Certified
⚠ Testosterone claims extrapolated from postmenopausal women data — not proven in young men [2]
⚠ UL: 20 mg/day — do not exceed [1]
⚠ Reasonable in bone health stack (Ca + D3 + K2 + Mg + boron) [1]
ℹ️ Not obtained from food. A trace element from fruit, vegetables and nuts; no formal daily dietary target is established.
🔬 Lab interpreter
Recommended test
No standard monitoring
Reference range / target
N/A
When to test
N/A [1].
Not routinely measured [1].
Full lab monitoring ↓
⚕ For professionals — confirm ranges against your local laboratory.
Clinical verdict
Boron is 'probably essential' — reduces urinary Ca/Mg losses, supports vitamin D, and may reduce SHBG. The testosterone marketing is extrapolated from a postmenopausal women study — NOT proven in young men. 3–6 mg/day is reasonable in a bone health stack. UL: 20 mg/day [1] [2].
1 How much do I need?
👤 Adults: Specific dosage data under clinical review
👴 Elderly: Specific dosage data under clinical review
🤰 Pregnancy: See guidance
No supplementation data. Dietary intake safe [1].
👦 Pediatric: See guidance
No supplementation data [1].
🏃 Athletes: Standard dose
⚖️ Obesity: Standard dose
Fat-soluble compounds may require dose adjustment in obesity.
🩺 Renal: Consult specialist
Dose adjustment may be needed in renal impairment.
🌱 Vegan: Standard dose

How to take

🍽 Timing: Any time [1].
💊 With food: With or without food [1].
🚫 Avoid: >20 mg/day (UL) [1].
2 Which form?
FormBioavailabilityVeganCost
['Boron glycinate', 'preferred', 'Chelated. Well-absorbed [1].']StandardCheck label
['Boron citrate', 'common', 'Good bioavailability [1].']StandardCheck label
['Borax (sodium borate)', '', 'NOT recommended as supplement — industrial chemical [1].']StandardCheck label
3 Common questions
Does boron boost testosterone? ▼
The 1987 USDA study showed increased testosterone in BORON-DEPLETED postmenopausal women. This has been extrapolated to young men — which is NOT supported by data. Boron may reduce SHBG modestly, but dramatic testosterone claims are overstated [2].
Should I take boron for bones? ▼
Reasonable as part of a bone health stack (with Ca, D3, K2, Mg). Boron reduces urinary Ca/Mg losses and supports vitamin D metabolism. 3–6 mg/day is sufficient [1] [2].
Is boron essential? ▼
Not officially classified as essential by IOM, but 'probably essential' based on accumulating evidence. No RDA exists; there is a UL of 20 mg/day [1].
4 Clinical evidence

Strong

Reduces urinary calcium and magnesium excretion in controlled metabolic studies (USDA) [2]. Involved in vitamin D metabolism [1]. HIGH

Moderate

Bone health: supplementation improved bone density markers in postmenopausal women in the USDA study [2]. Hormone modulation: reduced SHBG → increased free estradiol and testosterone in boron-depleted postmenopausal women [2]. Anti-inflammatory: reduced CRP in some small studies [1]. Arthritis: epidemiological association (low-boron areas have higher OA rates) [1]. MODERATE

Insufficient

Testosterone boosting in young men (extrapolated from postmenopausal data) [2]. Cancer prevention [1]. Cognitive function [1]. Wound healing [1]. LOW
5 Safety, toxicity & adverse events

Relative

⚠ Hormone-sensitive conditions — boron may increase estradiol; use caution in estrogen-receptor-positive cancers
⚠ Renal impairment — reduced boron excretion

🚩 Red flags

● Patient taking borax as supplement — NOT safe [1]
● Exceeding 20 mg/day UL [1]
6 Interactions

Drug interactions

Estrogen therapy Minor
Mechanism: Boron may increase estradiol levels. [2]
Effect: Additive estrogenic effect. [2]
Action: Monitor [2].

Supplement synergies

Calcium + D3 + K2 + Magnesium · Standard bone stack doses
Comprehensive bone health foundation [1] [2].
7 Regulatory
United States (IOM): No RDA. UL: 20 mg/day [1].
United States (FDA): Dietary supplement [1].
8 US supplement products
1,039
on-market products containing Boron (NIH DSLD)

Brands carrying Boron (285)

Click a brand to see its Boron products.
Or browse all 1,039 products in one list →
9 Frequently paired with
Magnesium 897 sharedCalcium 877 sharedZinc 829 sharedVitamin D 829 sharedManganese 805 sharedVitamin C 767 sharedChromium 712 sharedSelenium 704 shared
Boron vs CalciumBoron vs Vitamin D
10 Cite this page
Vancouver: Pkhakadze G. Boron — safety profile [Internet]. Tbilisi: PHIG; 2026 [cited 2026 Aug 31]. Available from: https://supplement.ge/ingredients/boron/
APA 7th: Pkhakadze, G. (2026). Boron — Safety profile. Public Health Institute of Georgia. https://supplement.ge/ingredients/boron/
📋 Editorial information
Author: Prof. G. Pkhakadze, MD, MPH, PhD
Affiliation: David Tvildiani Medical University (DTMU)
First published: January 2026
Last reviewed: 2026-05-29
Next review: March 2027
References: 2 cited sources
COI: SupplementIndex receives no funding from supplement manufacturers. All content independently authored by PHIG.
Process: Systematic literature review
📄 License & reuse
Published under Creative Commons Attribution 4.0 International (CC BY 4.0). You may share and adapt for any purpose with attribution.
Pkhakadze G. "Boron — Safety Profile." SupplementIndex, PHIG, 2026. https://supplement.ge/ingredients/boron/ CC BY 4.0.
GP
Prof. G. Pkhakadze, MD, MPH, PhD
Professor of Public Health · Head of Department, DTMU
Editor-in-Chief, Georgian Medical Journal (ISSN 3088-4322)
Chair, Public Health Institute of Georgia · UEMS Public Health Section
Educational and public health purposes. CC BY 4.0. Consult your healthcare provider before starting any supplement. Corrections: info@accreditation.ge. Publisher: PHIG
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