1 Product identity

Ingredient risk

Contains a high-risk ingredient

Cardio-Klenz

Name: Cardio-Klenz
Brand: Xtendlife

BrandXtendlife→Other Combinations Tablet or Pill 61 ingredients 1 high-risk 4 caution DSLD #17014

Net contents: 120 Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-01-25

2 Ingredients (61)

IngredientGroupSafety

CaloriesCalories—

Calories from FatCalories—

Vitamin CVitamin CGenerally Safe

Vitamin EVitamin EConditionally Safe

Vitamin KVitamin K (unspecified)—

RiboflavinRiboflavinGenerally Safe

NiacinNiacinConditionally Safe

Vitamin B6Vitamin B6 (unspecified)Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

Pantothenic AcidPantothenic AcidGenerally Safe

CalciumCalciumConditionally Safe

PhosphorusPhosphorusGenerally Safe

MagnesiumMagnesiumUse with Caution

ZincZincUse with Caution

SeleniumSeleniumConditionally Safe

ChromiumChromiumConditionally Safe

PotassiumPotassiumConditionally Safe

TaurineTaurineGenerally Safe

L-Arginine HydrochlorideArginine—

Mahonia extractMahonia (unspecified)—

Terminalia extractTerminalia—

Green Tea extractGreen Tea—

L-Lysine HydrochlorideLysine—

L-MethionineMETHIONINE—

MSMMethylsulfonylmethaneGenerally Safe

HesperidinHesperidin—

Grape seed extractGrape —

Alpha Lipoic AcidAlpha Lipoic Acid—

BromelainBromelainConditionally Safe

Butcher's BroomButcher's BroomConditionally Safe

Hawthorn extractHawthornConditionally Safe

Soy Lecithinlecithin—

L-ValineValine—

Zizyphus extractJujube —

N-Acetyl-L-CysteineN-Acetyl Cysteine—

Betain HCLBetaine Hydrochloride—

Choline BitartrateCholineGenerally Safe

InositolInositolHigh risk

Ginkgo extractGinkgo —

Grape skin extractGrape —

Nattozimes ProteaseProteolytic Enzymes (Proteases)—

Guggul Gum ExtractGuggulLimited Evidence

L-ProlineProline—

Red clover extractRed CloverConditionally Safe

Turmeric extractTurmericConditionally Safe

RutinRutin—

Coenzyme Q-10Coenzyme Q-10—

PiperinePiperine—

Trans-ResveratrolResveratrolConditionally Safe

reduced L-GlutathioneGlutathioneGenerally Safe

PolicosanolPolicosanol—

LipaseLipase—

Serrazimes ProteaseProteolytic Enzymes (Proteases)—

VinpocelineVinpocetine—

Microcrystalline CelluloseCellulose—

DextroseGlucose—

Silicon DioxideSiliconGenerally Safe

Sodium carboxymethyl CelluloseCarboxy Methyl Cellulose—

MaltodextrinMaltodextrin—

Enteric CoatingCoating—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]

⚠️ Use with caution — restricted in some markets

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].

3 Safety cross-reference

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Vitamin E — Conditionally Safe

⚠ Increased bleeding risk

⚠ All-cause mortality at >400 IU/day

Vitamin K — Limited Evidence

⚠ Critical interaction with warfarin

Riboflavin — Generally Safe

⚠ Harmless yellow urine

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Pantothenic Acid — Generally Safe

⚠ Diarrhea at very high doses

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Phosphorus — Generally Safe

⚠ Excess impairs calcium absorption

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Zinc — Use with Caution

⚠ Copper deficiency at >40 mg/day

⚠ Nausea, metallic taste

Selenium — Conditionally Safe

⚠ Selenosis >400 mcg

⚠ Diabetes risk at high doses

Chromium — Conditionally Safe

⚠ Hypoglycemia with diabetes meds

⚠ Rare renal/hepatic toxicity

Potassium — Conditionally Safe

⚠ Hyperkalemia risk

⚠ Dangerous with ACE inhibitors

Taurine — Generally Safe

⚠ May lower blood pressure

Chloride — Limited Evidence

⚠ Co-ingested with sodium

Green Tea Extract — Limited Evidence

⚠ HEPATOTOXICITY >800 mg EGCG

⚠ Iron absorption inhibition

L-Methionine — Limited Evidence

⚠ Raises homocysteine levels

⚠ May promote tumor growth

Methylsulfonylmethane — Generally Safe

⚠ GI effects

⚠ Headache

Grape Seed Extract — Limited Evidence

⚠ Antiplatelet effect

⚠ May interact with anticoagulants

Bromelain — Conditionally Safe

⚠ Increased bleeding risk

⚠ GI upset

Butcher's Broom — Conditionally Safe

⚠ GI upset

⚠ May interact with alpha-blockers

Hawthorn — Conditionally Safe

⚠ Additive with digoxin

⚠ Hypotension

Choline — Generally Safe

⚠ Fishy odor at high doses

Inositol — High risk

⚠ GI disturbance at high doses (>12 g)

⚠ May lower blood glucose

Guggul — Limited Evidence

⚠ GI upset, headache

⚠ Thyroid stimulation

L-Proline — Limited Evidence

⚠ Well tolerated

⚠ Important for collagen synthesis

Red Clover — Conditionally Safe

⚠ Estrogenic (isoflavones)

⚠ May increase bleeding risk

Resveratrol — Conditionally Safe

⚠ Estrogenic activity

⚠ CYP enzyme inhibition

Glutathione — Generally Safe

⚠ Limited oral bioavailability data

⚠ May affect zinc levels

Silicon — Generally Safe

⚠ Very low toxicity

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID17014

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-01-25

6 More from Xtendlife

View Xtendlife Safety Scorecard → 11 products

Arthrit-Eze Bone-Protec Cholest-Natural CX8 Diabet-Eze Female Rejuvenator

7 Cite this page

Vancouver

Pkhakadze G. Cardio-Klenz — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/cardio-klenz-17014/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG