1 Product identity

Ingredient risk

4 ingredients to use with caution

Arthrit-Eze

Name: Arthrit-Eze
Brand: Xtendlife

BrandXtendlife→Other Combinations Tablet or Pill 41 ingredients 4 caution DSLD #17012

Net contents: 90 Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-01-25

2 Ingredients (41)

IngredientGroupSafety

CaloriesCalories—

Calories from FatCalories—

Vitamin D3Vitamin DUse with Caution

Vitamin EVitamin EConditionally Safe

NiacinNiacinConditionally Safe

PhosphorusPhosphorusGenerally Safe

ZincZincUse with Caution

SeleniumSeleniumConditionally Safe

CopperCopperConditionally Safe

ManganeseManganeseConditionally Safe

PotassiumPotassiumConditionally Safe

Glucosamine SulfateGlucosamine Sulfate—

MSMMethylsulfonylmethaneGenerally Safe

Chondroitin SulfateChondroitin Sulfate—

Boswellia extractBoswelliaGenerally Safe

Turmeric extractTurmericConditionally Safe

ChitinChitin—

Corktree extractCorktree (unspecified)—

Ginger extractGinger —

Glucosamine HydrochlorideGlucosamine Hydrochloride—

RutinRutin—

SAMeSAMeConditionally Safe

from 294 mg S-Adenosylmethionine tosylateSAMeConditionally Safe

Celery seed extractcelery—

Green-Lipped Mussel powderNew Zealand green-lipped mussel—

L-ProlineProline—

Chasteberry extractChastetree—

PiperinePiperine—

Cetyl MyristoleateCetyl MyristoleateConditionally Safe

SiliconSiliconGenerally Safe

StrontiumStrontiumUse with Caution

BoronBoronConditionally Safe

Enzyme BlendBlend (non-nutrient/non-botanical)—

Microcrystalline CelluloseCellulose—

DextroseGlucose—

Enteric CoatingCoating—

Silicon DioxideSiliconGenerally Safe

MaltodextrinMaltodextrin—

Sodium Carboxymethyl CelluloseCarboxy Methyl Cellulose—

Corn StarchStarch—

Magnesium StearateMagnesium stearateUse with Caution

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].

Strontium — Strontium ranelate restricted to severe osteoporosis only. Cardiovascular contraindications.

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Vitamin E — Conditionally Safe

⚠ Increased bleeding risk

⚠ All-cause mortality at >400 IU/day

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Phosphorus — Generally Safe

⚠ Excess impairs calcium absorption

Zinc — Use with Caution

⚠ Copper deficiency at >40 mg/day

⚠ Nausea, metallic taste

Selenium — Conditionally Safe

⚠ Selenosis >400 mcg

⚠ Diabetes risk at high doses

Copper — Conditionally Safe

⚠ Hepatotoxicity at high doses

Manganese — Conditionally Safe

⚠ Neurotoxicity with chronic excess

Potassium — Conditionally Safe

⚠ Hyperkalemia risk

⚠ Dangerous with ACE inhibitors

Glucosamine — Limited Evidence

⚠ Shellfish allergy

⚠ May affect glucose

Methylsulfonylmethane — Generally Safe

⚠ GI effects

⚠ Headache

Chondroitin — Limited Evidence

⚠ May enhance anticoagulants

Boswellia — Generally Safe

⚠ GI discomfort

⚠ May enhance anticoagulants

Ginger Extract — Limited Evidence

⚠ May increase bleeding risk at high doses

⚠ Heartburn

Chloride — Limited Evidence

⚠ Co-ingested with sodium

SAMe — Conditionally Safe

⚠ Mania in bipolar

⚠ Serotonin syndrome with SSRIs

L-Proline — Limited Evidence

⚠ Well tolerated

⚠ Important for collagen synthesis

Cetyl Myristoleate — Conditionally Safe

⚠ Limited human data

⚠ GI effects

Silicon — Generally Safe

⚠ Very low toxicity

Strontium — Use with Caution

⚠ Competes with calcium absorption

⚠ Strontium ranelate: cardiovascular risk (Rx form)

Boron — Conditionally Safe

⚠ Reproductive toxicity in animals

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

4 Label claims

• Nutrient

• All Other

• Structure/Function

5 Data source

DSLD ID17012

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-01-25

6 More from Xtendlife

View Xtendlife Safety Scorecard → 11 products

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7 Cite this page

Vancouver

Pkhakadze G. Arthrit-Eze — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/arthrit-eze-17012/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG