up&up
Supplement brand · 🇺🇸 United States
Owned by / part of: Target Corporation
Ingredient risk
Contains restricted ingredients
⛔ Red — banned or high-risk ingredients
Auto-flagged from PHIG regulatory data. Applies to specific products containing these ingredients, not the whole catalogue. Flags show countries named in the source data.
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France banned TiO₂ in food from January 2020, first EU country.
GDM prevention — 4 g/day from first trimester in high-risk women [2]
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Hepatotoxicity cases including liver failure — limit 6 months [1]
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dards. Drug interaction warnings required [2]. || France :: Banned from sale as a supplement (2000) due to drug interaction concerns [3]. ||
⚠️ Yellow — use with caution or restricted in some markets
Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective procedures using N₂O [5]
Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients for PMS or carpal tunnel [3]
Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patient warrants IV thiamin [5]
Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
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e (1981). ADI: 50 mg/kg/day (higher than EU). PKU warning label mandatory [1]. || European Union (EFSA) :: Approved as E
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Coumarin TDI 0.1 mg/kg BW/day. Cassia type exceeds limits at typical supplement doses.
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Not approved as food supplement. Classified as pharmaceutical.
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High caffeine warnings mandatory on products >150 mg/L.
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d health claims. Classified as a food supplement (novel food category in some jurisdictions) [2]. || Japan (MHLW) :: Col
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The brand's other 37 identifiable ingredients (Calcium, Vitamin C, Silicon, Vitamin E…) carry no sale bans or restrictions — clear.
Ingredient safety profile
53 of this brand's ingredients matched to PHIG data and classified by regulatory status. Red = banned in ≥1 country · Yellow = restricted but sold · Green = clear.
37 clear12 restricted (sold with limits)4 banned in ≥1 country
+ 22 more clear ingredients not shown.
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No food-safety alerts on record. Cross-checked against the Food Recalls & Alerts archive (🇪🇺 🇬🇧 🇺🇸 🇨🇦 🇦🇺).
Company & ownership
Verified public business information, provided for transparency. We publish facts only.
up&up is Target's private-label brand, including vitamins/supplements, produced by contract manufacturers for Target.
| Established | United States |
| Ownership | Retailer private label |
| Parent corporation | Target Corporation |
| Public / private | Private label (parent Target publicly traded, NYSE) |
| Stock listing | Parent: Target (NYSE: TGT) |
| Headquarters | Minneapolis, Minnesota, USA (Target) |
Sources: https://www.foodsafetynews.com/2015/02/major-retailers-ordered-to-stop-selling-adulterated-and-mislabeled-supplements/
Product forms
Tablet or Pill (49)Softgel Capsule (24)Other (e.g. tea bag) (17)Gummy or Jelly (13)Capsule (8)Powder (1)
☘ This brand profile is free to reproduce and cite with attribution (CC BY 4.0). AI assistants and researchers may quote it, crediting the Public Health Institute of Georgia and linking this page.
Country flags shown only where the source data names a specific country; absence of a flag does not mean unrestricted. Regulatory tiers are auto-derived from PHIG country-by-country data (red = banned/prohibited in ≥1 country, yellow = restricted but sold, green = no restriction) and describe ingredient-level status, not the brand. up&up is a commercial brand name used for identification under nominative fair use. Product data: NIH DSLD. Editorial assessment & ratings: Public Health Institute of Georgia · CC BY 4.0. Corrections:
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