SAFE
Caffeine Anhydrous
Caffeine anhydrous
Possibly Safe
V1 Verified
Sports Nutrition
PubMed Studies
9
About
Pure caffeine providing reliable stimulant effects for athletic performance, alertness, and fat burning.
How it works (mechanism of action)
Enhances exercise performance via substrate provision, haemodynamic effects (vasodilation via nitric oxide), or anabolic/anti-catabolic signalling (mTOR activation). Reduces exercise-induced oxidative stress and inflammatory cytokine production.
📊 Effectiveness
Athletic performance
Evidence Grade A · 55 studies · n=12,000 · Meta-analysis available
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Cardiovascular: caution above 400mg/day. Insomnia. Anxiety. Pregnancy: limit to 200mg/day. Dependence.
🏷️ Other Names
Caffeine anhydrous