ON Optimum Nutrition
Supplement brand · 🇺🇸 United States · est. 1986
Owned by / part of: Glanbia plc (Ireland) — Glanbia Performance Nutrition
Ingredient risk
Contains restricted ingredients
⛔ Red — banned or high-risk ingredients
Auto-flagged from PHIG regulatory data. Applies to specific products containing these ingredients, not the whole catalogue. Flags show countries named in the source data.
GDM prevention — 4 g/day from first trimester in high-risk women [2]
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France banned TiO₂ in food from January 2020, first EU country.
⚠️ Yellow — use with caution or restricted in some markets
Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective procedures using N₂O [5]
Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patient warrants IV thiamin [5]
Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients for PMS or carpal tunnel [3]
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High caffeine warnings mandatory on products >150 mg/L.
Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
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Coumarin TDI 0.1 mg/kg BW/day. Cassia type exceeds limits at typical supplement doses.
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Not approved as food supplement. Classified as pharmaceutical.
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The brand's other 46 identifiable ingredients (Sucralose, Sodium, Calcium, Vitamin C…) carry no sale bans or restrictions — clear.
Ingredient safety profile
58 of this brand's ingredients matched to PHIG data and classified by regulatory status. Red = banned in ≥1 country · Yellow = restricted but sold · Green = clear.
46 clear10 restricted (sold with limits)2 banned in ≥1 country
+ 31 more clear ingredients not shown.
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No food-safety alerts on record. Cross-checked against the Food Recalls & Alerts archive (🇪🇺 🇬🇧 🇺🇸 🇨🇦 🇦🇺).
Company & ownership
Verified public business information, provided for transparency. We publish facts only.
Optimum Nutrition (ON), the world's #1 sports-nutrition (whey protein) brand. Acquired by Irish global-nutrition group Glanbia plc in 2008; part of Glanbia Performance Nutrition.
| Established | 1986 · Illinois, United States |
| Ownership | Subsidiary |
| Parent corporation | Glanbia plc (Ireland) — Glanbia Performance Nutrition |
| Public / private | Private (parent Glanbia plc publicly traded, Dublin/London) |
| Stock listing | Parent: Glanbia plc (ISE/LSE: GLB / GLAPF) |
| Headquarters | Downers Grove, Illinois, USA |
Sources: https://en.wikipedia.org/wiki/Glanbia | https://www.linkedin.com/company/glanbiaperformancenutrition
Product forms
Powder (65)Capsule (10)Tablet or Pill (8)Softgel Capsule (5)
☘ This brand profile is free to reproduce and cite with attribution (CC BY 4.0). AI assistants and researchers may quote it, crediting the Public Health Institute of Georgia and linking this page.
Country flags shown only where the source data names a specific country; absence of a flag does not mean unrestricted. Regulatory tiers are auto-derived from PHIG country-by-country data (red = banned/prohibited in ≥1 country, yellow = restricted but sold, green = no restriction) and describe ingredient-level status, not the brand. ON Optimum Nutrition is a commercial brand name used for identification under nominative fair use. Product data: NIH DSLD. Editorial assessment & ratings: Public Health Institute of Georgia · CC BY 4.0. Corrections:
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