1 Product identity
Ingredient risk
Contains a high-risk ingredient
Special One
BrandNOW→Other Combinations Tablet or Pill 50 ingredients 1 high-risk 7 caution DSLD #15678Net contents: 30 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2012-11-21
2 Ingredients (50)
IngredientGroupSafety
PABAPABA—
organic BarleyBarley—
LipaseLipase—
RutinRutin—
Citrus BioflavonoidsFlavonoid (mixture)—
Glutamic AcidGlutamic Acid—
AmylaseAmylase—
LycopeneLycopene—
Alpha Lipoic AcidAlpha Lipoic Acid—
CelluloseCellulose—
Stearic AcidStearic Acid—
ChlorophyllChlorophyll—
Vegetable CoatingCoating—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Choline — Generally Safe
⚠ Fishy odor at high doses
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Vanadium — Limited Evidence
⚠ GI toxicity: nausea, vomiting, diarrhea
⚠ Green tongue
Spirulina — Limited Evidence
⚠ Contamination risk: microcystins, heavy metals
⚠ Autoimmune stimulation
Chlorella — Generally Safe
⚠ Contamination risk
⚠ May affect warfarin (vitamin K content)
Betaine HCl — Limited Evidence
⚠ Heartburn, GI burning if used without protein meals
⚠ Not for those on H. pylori treatment
Papain — Conditionally Safe
⚠ Allergic reactions
⚠ Increased bleeding risk
Bromelain — Conditionally Safe
⚠ Increased bleeding risk
⚠ GI upset
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Sodium — Limited Evidence
⚠ Hypertension
⚠ Fluid retention
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
5 Data source
DSLD ID15678
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2012-11-21
6 More from NOW
View NOW Safety Scorecard → 1,261 products
"Green" Black Walnut Wormwood Complex100% Natural Hawaiian Spirulina Powder4x6 Acidophilus4x6 Acidophilus4x6 Acidophilus Powder5-HTP 100 mg7 Cite this page
Vancouver
Pkhakadze G. Special One — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 28]. Available from: https://supplement.ge/products/special-one-15678/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG