PubMed Studies
4
PubChem CID
About
HCl source for hypochlorhydria. Used for protein digestion, B12 absorption, and low stomach acid.
How it works (mechanism of action)
Catalyses hydrolysis of specific food macromolecules (proteins, carbohydrates, fats, or plant cell wall components) facilitating nutrient absorption. Reduces GI symptoms of malabsorption including bloating, flatulence, and loose stools.
📊 Effectiveness
Homocysteine reduction
Evidence Grade A · 18 studies · n=2,800 · Meta-analysis available
Hypochlorhydria
Evidence Grade B · 10 studies · n=880
Athletic performance
Evidence Grade B · 14 studies · n=1,400
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Peptic ulcers: contraindicated. Heartburn/GERD: avoid if excess acid is the cause.
💊 Drug Interactions (1)
⚪ Antidiabetic drugs
MinorAntidiabetic
Management: Monitor blood glucose.
🇪🇺 EU Health Claims Status
Art.13(1)
✓ AuthorisedThe claim may be used only for food which contains at least 500 mg of betaine per quantified portion. In order to bear the claim information shall be given to the consumer that the beneficial effect is obtained with a daily intake of 1,5 g of betaine. In order to bear the claim information shall be given to the consumer that a daily intake in excess of 4 g may significantly increase blood cholesterol levels.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
Betaine hydrochloride