1 Product identity

Ingredient risk

Contains a high-risk ingredient

Metabolic Cleanse

Name: Metabolic Cleanse
Brand: Douglas Laboratories

BrandDouglas Laboratories→Other Combinations Powder 75 ingredients 1 high-risk 6 caution DSLD #9488

Net contents: 873.5 g

Target: Adults and Children 4 years and above

DSLD entry: 2012-06-25

2 Ingredients (75)

IngredientGroupSafety

CaloriesCalories—

Calories from FatCalories—

Total FatFat (unspecified)—

Saturated FatSaturated fat—

CholesterolCholesterol—

SodiumSodiumConditionally Safe

Total CarbohydratesCarbohydrate—

Dietary FiberFiber (unspecified)—

SugarSugar—

ProteinProtein (unspecified)—

Each Serving Also Provides ApproximatelyBlend—

Vitamin A/Beta Carotene complexBlend (Combination)—

Vitamin CVitamin CGenerally Safe

Vitamin DVitamin DUse with Caution

Vitamin EVitamin EConditionally Safe

ThiamineThiaminUse with Caution

RiboflavinRiboflavinGenerally Safe

Niacin/NiacinamideVitamin B3 (mixed)—

Vitamin B-6Vitamin B6 (unspecified)Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

BiotinBiotinGenerally Safe

Pantothenic AcidVitamin B5—

CalciumCalciumConditionally Safe

PhosphorusPhosphorusGenerally Safe

IodineIodineConditionally Safe

MagnesiumMagnesiumUse with Caution

ZincZincUse with Caution

ManganeseManganeseConditionally Safe

ChromiumChromiumConditionally Safe

MolybdenumMolybdenumGenerally Safe

PotassiumPotassiumConditionally Safe

L-GlutamineGlutamineConditionally Safe

N-Acetyl L-Cysteine/L-Cysteine ComplexBlend (Combination)—

Betaine HClBetaine Hydrochloride—

CholineCholineGenerally Safe

BioflavonoidsFlavonoid (mixture)—

InositolInositolHigh risk

PABAPABA—

Glutamic Acid HydrochlorideGlutamic Acid—

L-MethionineMETHIONINE—

BoronBoronConditionally Safe

Trace MineralsBlend (Combination)—

VanadiumVanadiumLimited Evidence

Proprietary BlendProprietary Blend (Combination)—

Grape Seed extractGrape —

MSMMethylsulfonylmethaneGenerally Safe

N-Acetyl L-CysteineN-Acetyl Cysteine—

Red wine proanthocyanidinsProanthocyanidins (unspecified)—

Typical Amino Acid Profile:Header—

Aspartic AcidAspartic Acid—

Glutamic AcidGlutamic Acid—

LeucineLeucine—

ArginineArginine—

TyrosineTyrosine—

PhenylalaninePhenylalanine—

IsoleucineIsoleucine—

SerineSerine—

GlycineGlycineGenerally Safe

ThreonineTHREONINE—

MethionineMETHIONINE—

LysineLysine—

HistidineHistidine—

TryptophanTryptophan—

CysteineCysteine—

ValineValine—

AlanineAlanine—

Rice Protein isolateRice ProteinGenerally Safe

Pea ProteinPea proteinGenerally Safe

Medium-Chain TriglyceridesMedium chain triglycerides (MCT)—

organic evaporated CaneSugar cane—

Rice syrupRice—

natural Red Raspberry flavorRed Raspberry—

SeacureTBD—

FOSFructo-Oligosaccharides—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].

3 Safety cross-reference

Sodium — Conditionally Safe

⚠ Hypertension

⚠ Fluid retention

Vitamin A — Limited Evidence

⚠ Teratogenic at high doses

⚠ Hepatotoxic with chronic excess

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Vitamin E — Conditionally Safe

⚠ Increased bleeding risk

⚠ All-cause mortality at >400 IU/day

Thiamin — Use with Caution

⚠ Very low toxicity

Riboflavin — Generally Safe

⚠ Harmless yellow urine

Niacin — Limited Evidence

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Biotin — Generally Safe

⚠ Interferes with troponin and thyroid lab assays

Pantothenic Acid — Limited Evidence

⚠ Diarrhea at very high doses

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Phosphorus — Generally Safe

⚠ Excess impairs calcium absorption

Iodine — Conditionally Safe

⚠ Thyroid dysfunction at excess

⚠ Kelp: variable content

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Zinc — Use with Caution

⚠ Copper deficiency at >40 mg/day

⚠ Nausea, metallic taste

Manganese — Conditionally Safe

⚠ Neurotoxicity with chronic excess

Chromium — Conditionally Safe

⚠ Hypoglycemia with diabetes meds

⚠ Rare renal/hepatic toxicity

Molybdenum — Generally Safe

⚠ Very low toxicity

Potassium — Conditionally Safe

⚠ Hyperkalemia risk

⚠ Dangerous with ACE inhibitors

L-Glutamine — Conditionally Safe

⚠ Hepatic encephalopathy risk

⚠ May elevate ammonia

Betaine HCl — Limited Evidence

⚠ Heartburn, GI burning if used without protein meals

⚠ Not for those on H. pylori treatment

Choline — Generally Safe

⚠ Fishy odor at high doses

Inositol — High risk

⚠ GI disturbance at high doses (>12 g)

⚠ May lower blood glucose

Chloride — Limited Evidence

⚠ Co-ingested with sodium

L-Methionine — Limited Evidence

⚠ Raises homocysteine levels

⚠ May promote tumor growth

Boron — Conditionally Safe

⚠ Reproductive toxicity in animals

Vanadium — Limited Evidence

⚠ GI toxicity: nausea, vomiting, diarrhea

⚠ Green tongue

Grape Seed Extract — Limited Evidence

⚠ Antiplatelet effect

⚠ May interact with anticoagulants

Methylsulfonylmethane — Generally Safe

⚠ GI effects

⚠ Headache

Glycine — Generally Safe

⚠ Well tolerated

Rice Protein — Generally Safe

⚠ Lower in lysine

⚠ Arsenic contamination risk in some brands

Pea protein — Generally Safe

⚠ Lower in methionine

⚠ GI discomfort in some

4 Label claims

• All Other

5 Data source

DSLD ID9488

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2012-06-25

6 More from Douglas Laboratories

View Douglas Laboratories Safety Scorecard → 788 products

A-Potene 10 A-Potene 25 A-Retic Natural Herbal Formula A-Retic Natural Herbal Formula A.R. Formula A.R.M.D. Eye Support

7 Cite this page

Vancouver

Pkhakadze G. Metabolic Cleanse — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/dsld-9488/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG