Metagenics

Supplement brand · 🇺🇸 United States · est. 1983
Owned by / part of: Gryphon Investors (US private equity, since 2021)
Ingredient risk
Contains restricted ingredients
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⛔ Red — banned or high-risk ingredients

Auto-flagged from PHIG regulatory data. Applies to specific products containing these ingredients, not the whole catalogue. Flags show countries named in the source data.
Xylitolin 6 products
Dog owner not warned about xylitol toxicity — potentially fatal to dogs [1]
Inositolin 2 products
GDM prevention — 4 g/day from first trimester in high-risk women [2]
Ashwagandhain 1 products
🇩🇰 🇧🇪 🇪🇺
Banned April 2023 following DTU risk assessment. All products withdrawn.
DHEAin 1 products
🇨🇦 🇬🇧 🇪🇺 🇦🇺
Not approved for OTC sale as supplement.
St. John's Wortin 1 products
🇫🇷 🇯🇵 🇰🇷
dards. Drug interaction warnings required [2]. || France :: Banned from sale as a supplement (2000) due to drug interaction concerns [3]. ||

⚠️ Yellow — use with caution or restricted in some markets

Magnesiumin 61 products
Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Vitamin Din 24 products
Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Zincin 22 products
Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Vitamin B6in 17 products
Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients for PMS or carpal tunnel [3]
Vitamin B12in 16 products
Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective procedures using N₂O [5]
Thiaminin 14 products
Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patient warrants IV thiamin [5]
Ironin 8 products
Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
The brand's other 57 identifiable ingredients (Silicon, Calcium, Vitamin E, Phosphorus…) carry no sale bans or restrictions — clear.

Overview

118
Products on market
319
Unique ingredients
5
Product forms

Ingredient safety profile

69 of this brand's ingredients matched to PHIG data and classified by regulatory status. Red = banned in ≥1 country · Yellow = restricted but sold · Green = clear.
57 clear7 restricted (sold with limits)5 banned in ≥1 country
IngredientRestricting countriesStatusProducts
XylitolBanned somewhere6
InositolBanned somewhere2
Ashwagandha🇩🇰 🇧🇪 🇪🇺Banned somewhere1
DHEA🇨🇦 🇬🇧 🇪🇺 🇦🇺Banned somewhere1
St. John's Wort🇫🇷 🇯🇵 🇰🇷Banned somewhere1
MagnesiumRestricted61
Vitamin DRestricted24
ZincRestricted22
Vitamin B6Restricted17
Vitamin B12Restricted16
ThiaminRestricted14
IronRestricted8
SiliconClear67
CalciumClear41
Vitamin EClear35
PhosphorusClear31
Vitamin CClear27
NiacinClear19
Fish Oil (general)Clear15
ChromiumClear14
PotassiumClear14
SodiumClear14
ManganeseClear13
RiboflavinClear13
Vitamin AClear12
CopperClear11
SeleniumClear10
+ 42 more clear ingredients not shown.
🛡️
No food-safety alerts on record. Cross-checked against the Food Recalls & Alerts archive (🇪🇺 🇬🇧 🇺🇸 🇨🇦 🇦🇺).

Company & ownership

Verified public business information, provided for transparency. We publish facts only.

Practitioner-channel / nutrigenomics supplement and medical-foods company founded 1983 (some sources 1985). Previously owned by Amway parent Alticor; acquired by US private-equity firm Gryphon Investors in 2021. Certified B Corp since 2022.

Established1983 · California, United States
OwnershipSubsidiary (private-equity owned)
Parent corporationGryphon Investors (US private equity, since 2021)
Public / privatePrivate
HeadquartersAliso Viejo, California, USA
Sources: https://www.cbinsights.com/company/metagenics | https://ethical.org.au/companies/1857
Are you a representative of Metagenics? Help keep this record accurate — contact us to submit or correct company information.

Product forms

Tablet or Pill (62)Softgel Capsule (26)Powder (16)Liquid (7)Capsule (7)

Products (118 total)

ProductFormFlag
ActiFolateTablet or Pill
AdvaClearCapsule
Arginine PlusTablet or Pill
Axis Endo Mango FlavorPowder
Azeo-PangenTablet or Pill
Azeo-PangenTablet or Pill
Azeo-Pangen Extra StrengthTablet or Pill
Bone Builder ActiveTablet or Pill
Bone Builder with MagnesiumTablet or Pill
C-UltratabsTablet or Pill
Cal ApatiteTablet or Pill
Cal Apatite 1000Tablet or Pill
View all 118 products →
☘ This brand profile is free to reproduce and cite with attribution (CC BY 4.0). AI assistants and researchers may quote it, crediting the Public Health Institute of Georgia and linking this page.
Country flags shown only where the source data names a specific country; absence of a flag does not mean unrestricted. Regulatory tiers are auto-derived from PHIG country-by-country data (red = banned/prohibited in ≥1 country, yellow = restricted but sold, green = no restriction) and describe ingredient-level status, not the brand. Metagenics is a commercial brand name used for identification under nominative fair use. Product data: NIH DSLD. Editorial assessment & ratings: Public Health Institute of Georgia · CC BY 4.0. Corrections: info@accreditation.ge