1 Product identity
Ingredient risk
7 ingredients to use with caution
Axis Endo Mango Flavor
BrandMetagenics→Other Combinations Powder 55 ingredients 7 caution DSLD #327629Net contents: 1.38 Ounce(s)
Target: Adults and Children 4 years and above
DSLD entry: 2025-06-25
2 Ingredients (55)
IngredientGroupSafety
CaloriesCalories—
Total FatFat (unspecified)—
Total CarbohydratesCarbohydrate—
Dietary FiberFiber (unspecified)—
Total SugarsSugar—
Added SugarsSugar—
ProteinProtein—
SilymarinSilymarin—
Proprietary Mix of CurcuminProprietary Blend (Herb/Botanical)—
CurcuminoidsCurcuminoid—
N-Acetyl L-CysteineN-Acetyl Cysteine—
Rosemary Leaf ExtractRosemary —
Secoisolariciresinol DiglucosideSecoisolariciresinol diglycoside—
Melon Pulp Juice Concentrate, DriedMelon—
Mixed Carotenoidscarotenoids—
Apple FiberApple fiber—
Guar Gum, HydrolyzedGuar—
Olive OilOlive Oil—
Medium Chain TriglycerideMedium chain triglycerides (MCT)—
Natural FlavorsFlavor—
Tapioca FlourStarch—
Mono and DiglyceridesBlend (Metabolite, constituent, extract, isolate, or combination of these)—
Monk Fruit extractLuo Han Guo—
Palm Oil, HydrogenatedPalm Oil—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Limited Evidence
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Vitamin K — Conditionally Safe
⚠ Critical interaction with warfarin
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Phosphorus — Generally Safe
⚠ Excess impairs calcium absorption
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Sodium — Conditionally Safe
⚠ Hypertension
⚠ Fluid retention
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Milk Thistle — Generally Safe
⚠ Mild GI
⚠ Asteraceae allergy
Fenugreek — Conditionally Safe
⚠ Hypoglycemia
⚠ Maple syrup odor
Pea protein — Generally Safe
⚠ Lower in methionine
⚠ GI discomfort in some
Rice Protein — Generally Safe
⚠ Lower in lysine
⚠ Arsenic contamination risk in some brands
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID327629
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2025-06-25
6 More from Metagenics
View Metagenics Safety Scorecard → 118 products
ActiFolateAdvaClearArginine PlusAzeo-PangenAzeo-PangenAzeo-Pangen Extra Strength7 Cite this page
Vancouver
Pkhakadze G. Axis Endo Mango Flavor — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 17]. Available from: https://supplement.ge/products/dsld-327629/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG