1 Product identity
Ingredient risk
4 ingredients to use with caution
N.O.-Xplode 2.0 Advanced Strength Fruit Punch
BrandBSN→Other Combinations Powder 57 ingredients 4 caution DSLD #33222Net contents: 2.48 lb
Target: Adults and Children 4 years and above
DSLD entry: 2014-05-23
2 Ingredients (57)
IngredientGroupSafety
CaloriesCalories—
Total CarbohydratesCarbohydrate—
SugarSugar—
N.O.-XPOLODE(TM) 2.0 PROPRIETARY BLENDProprietary Blend (Combination)—
Advanced Strength & Performance MatrixBlend—
Glucose PolymersGlucose polymer (unspecified)—
Creatinol-O-PhosphateCreatinol-O-Phosphate—
Malic AcidMalic Acid—
GlycocyamineGlycocyamine—
Guanidino Propionic AcidGuanidinopropionic Acid (GPA )—
Ener-Tropic XplosionBlend (Combination)—
GlucuronolactoneGlucuronolactone—
MCT'sMedium chain triglycerides (MCT)—
Lesser PeriwinkleCommon Periwinkle—
N.O. Meta-FusionProprietary Blend (Combination)—
L-Histidine-Alpha Ketoglutaric AcidHistidine alpha-ketoglutarate—
NADNicotinamide Adenine Dinucleotide—
GynostemmaJiaogulan—
Phospho-Electrolyte CompositeBlend (Combination)—
Glycerol Polymer ComplexBlend (non-nutrient/non-botanical)—
Glycerol StearateGlycerol Monostearate—
Citric AcidCitric Acid—
Natural & Artificial flavorsFlavor—
FD&C Red #40Color—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Caffeine (Anhydrous) 🇬🇧 🇪🇺 🇦🇺 — High caffeine warnings mandatory on products >150 mg/L.
3 Safety cross-reference
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Phosphorus — Generally Safe
⚠ Excess impairs calcium absorption
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Sodium — Conditionally Safe
⚠ Hypertension
⚠ Fluid retention
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Beta-Alanine — Generally Safe
⚠ Tingling (paraesthesia) — harmless
Creatine — Limited Evidence
⚠ Water retention
⚠ Weight gain
Betaine HCl — Limited Evidence
⚠ Heartburn, GI burning if used without protein meals
⚠ Not for those on H. pylori treatment
Cinnamon — Limited Evidence
⚠ Cassia: high coumarin (hepatotoxic)
⚠ May lower glucose
L-Tyrosine — Limited Evidence
⚠ May worsen hyperthyroidism
⚠ Migraine trigger in some
Taurine — Generally Safe
⚠ May lower blood pressure
Caffeine (Anhydrous) — Use with Caution
L-Arginine — Limited Evidence
⚠ Hypotension
⚠ May worsen herpes outbreaks
Citrulline malate — Generally Safe
⚠ May lower blood pressure
L-Citrulline — Limited Evidence
⚠ May lower blood pressure
Sucralose — Conditionally Safe
⚠ May affect gut microbiome
⚠ Heating may produce chlorinated compounds
4 Label claims
• All Other
5 Data source
DSLD ID33222
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2014-05-23
6 More from BSN
View BSN Safety Scorecard → 38 products
Amino X Fruit PunchAminoX EAAs Strawberry DragonfruitAminoX EAAs Watermelon SmashAromavexCellMassCellmass 2.0 Arctic Berry7 Cite this page
Vancouver
Pkhakadze G. N.O.-Xplode 2.0 Advanced Strength Fruit Punch — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 28]. Available from: https://supplement.ge/products/n-o-xplode-2-0-advanced-strength-fruit-punch-33222/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG