SAFE

Citrulline Malate

citrulline-malate
Possibly Safe V1 Verified
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PubMed Studies
38
PubChem CID
About

Citrulline converts to arginine in kidney — increases plasma arginine more efficiently than arginine supplementation; NO precursor; reduces ammonia during exercise; malate in Krebs cycle

How it works (mechanism of action)

Used for sports endurance, pump and performance in French gym supplements. Better than arginine for NO production. Eric Favre sport, Arkopharma sport.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

🇪🇺 EU Health Claims Status
Art.13(5)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 5
Art.13(5)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 5
Updated: 2026-04-02
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