1 Product identity
Ingredient risk
Contains restricted ingredients
Life Extension Mix Powder Without Copper
BrandLife Extension→Other Combinations Powder 72 ingredients 1 banned 1 high-risk 6 caution DSLD #62279Net contents: 420 Gram(s)
Target: Adults and Children 4 years and above
DSLD entry: 2016-07-25
2 Ingredients (72)
IngredientGroupSafety
PantethinePantethine—
N-Acetyl-L-CysteineN-Acetyl Cysteine—
Broccoli Concentrate BlendBroccoli—
Broccoli extractsBroccoli—
Acerola extractAcerola—
Fruit/Berry ComplexBlend (Herb/Botanical)—
Blackberry powderBlackberry—
Blueberry powderBlueberry—
Cherry powdercherry (unspecified)—
Cranberry powdercranberry—
Persimmon powderPersimmon—
Prune powderPlum—
Wild Blueberry Anthocyanin extractBlueberry—
Maqui berry (Aristotelia chilensis) Anthocyanin extractMaqui—
CherryPure Tart Cherry (Prunus cerasus) Proanthocyanidin extractSour Cherry—
Pomella Pomegranate extractPomegranate—
natural Mixed TocopherolsVitamin E (mixed tocopherols)—
Leucoselect Grape seed Proanthocyanidin extractGrape —
BioVin Grape Proanthocyanidin extractGrape —
DelphinidinsDelphinidin—
Marigold extractMarigold (unspecified)—
Trans-ZeaxanthinZeaxanthin—
Olive juice extractOlive —
LuteolinLuteolin—
LycopeneLycopene—
Cyanidin-3-GlucosideCyanidin—
Trans-PterostilbenePterostilbene—
NIAGEN Nicotinamide RibosideVitamin B3 (Nicotinamide riboside)—
MaltodextrinMaltodextrin—
natural Orange flavorOrange (unspecified)—
Stevia extractStevia—
Medium Chain TriglyceridesMedium chain triglycerides (MCT)—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⛔ Contains an ingredient banned in ≥1 country
Bitter Orange — but minimal α-1/α-2 activity (distinguishing it from the banned ephedrine) [1]. Despite widespread use in fat-burners and pre-workouts, c
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Limited Evidence
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Limited Evidence
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Taurine — Generally Safe
⚠ May lower blood pressure
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Choline — Limited Evidence
⚠ Fishy odor at high doses
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Glycine — Limited Evidence
⚠ Well tolerated
Bitter Orange — Banned in ≥1 country
⚠ Cardiovascular events when combined with caffeine
⚠ Hypertension, tachycardia
Calcium d-Glucarate — Generally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Green Tea Extract — Limited Evidence
⚠ HEPATOTOXICITY >800 mg EGCG
⚠ Iron absorption inhibition
Elderberry — Limited Evidence
⚠ Raw berries: cyanogenic glycosides
⚠ Cytokine storm concern
Milk Thistle — Generally Safe
⚠ Mild GI
⚠ Asteraceae allergy
Bromelain — Conditionally Safe
⚠ Increased bleeding risk
⚠ GI upset
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
SAMe — Limited Evidence
⚠ Mania in bipolar
⚠ Serotonin syndrome with SSRIs
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID62279
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2016-07-25
6 More from Life Extension
View Life Extension Safety Scorecard → 201 products
Acetyl-L-Carnitine ArginateAdrenal Energy FormulaAdvanced Cortisol BalanceAdvanced Oral HygieneAMAnti-Alcohol Complex7 Cite this page
Vancouver
Pkhakadze G. Life Extension Mix Powder Without Copper — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/life-extension-mix-powder-without-copper-62279/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG