Life Extension
Supplement brand · 🇺🇸 United States · est. 1980
Independent, privately owned
Ingredient risk
Contains restricted ingredients
⛔ Red — banned or high-risk ingredients
Auto-flagged from PHIG regulatory data. Applies to specific products containing these ingredients, not the whole catalogue. Flags show countries named in the source data.
Dog owner not warned about xylitol toxicity — potentially fatal to dogs [1]
GDM prevention — 4 g/day from first trimester in high-risk women [2]
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Banned April 2023 following DTU risk assessment. All products withdrawn.
but minimal α-1/α-2 activity (distinguishing it from the banned ephedrine) [1]. Despite widespread use in fat-burners and pre-workouts, c
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Not approved for OTC sale as supplement.
Use cautiously in severely immunocompromised patients, ICU patients, and those with central venous catheters — rare cases of probiotic bacteremia and fungemia reported [1].
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France banned TiO₂ in food from January 2020, first EU country.
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Hepatotoxicity cases including liver failure — limit 6 months [1]
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Not permitted in NHPs.
⚠️ Yellow — use with caution or restricted in some markets
Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective procedures using N₂O [5]
Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patient warrants IV thiamin [5]
Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients for PMS or carpal tunnel [3]
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Not approved as food supplement. Classified as pharmaceutical.
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d health claims. Classified as a food supplement (novel food category in some jurisdictions) [2]. || Japan (MHLW) :: Col
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ood. Dietary supplement [1]. || European Union :: Novel food ingredient [1]. || South Korea :: Dietary supplement. || Ma
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The brand's other 53 identifiable ingredients (Silicon, Calcium, Vitamin E, Vitamin C…) carry no sale bans or restrictions — clear.
Ingredient safety profile
71 of this brand's ingredients matched to PHIG data and classified by regulatory status. Red = banned in ≥1 country · Yellow = restricted but sold · Green = clear.
53 clear9 restricted (sold with limits)9 banned in ≥1 country
+ 38 more clear ingredients not shown.
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No food-safety alerts on record. Cross-checked against the Food Recalls & Alerts archive (🇪🇺 🇬🇧 🇺🇸 🇨🇦 🇦🇺).
Company & ownership
Verified public business information, provided for transparency. We publish facts only.
Life Extension is a privately owned vitamin and supplement company founded in 1980 by Saul Kent and William Faloon. HQ and retail store in Fort Lauderdale FL; Las Vegas customer service; New Jersey manufacturing/shipping. ~500 employees, 400+ products.
| Established | 1980 · Fort Lauderdale, Florida, United States |
| Ownership | Independent, privately owned |
| Public / private | Private (privately owned) |
| Headquarters | Fort Lauderdale, Florida, USA |
| Employees | ~500 |
| Market / revenue | Reported approaching ~$1 bn (third-party estimate) |
Sources: https://www.lifeextension.com/about/about-life-extension | https://en.wikipedia.org/wiki/Biomedical_Research__Longevity_Society
Product forms
Capsule (89)Softgel Capsule (38)Tablet or Pill (19)Lozenge (7)Powder (5)Liquid (4)Other (e.g. tea bag) (2)
☘ This brand profile is free to reproduce and cite with attribution (CC BY 4.0). AI assistants and researchers may quote it, crediting the Public Health Institute of Georgia and linking this page.
Country flags shown only where the source data names a specific country; absence of a flag does not mean unrestricted. Regulatory tiers are auto-derived from PHIG country-by-country data (red = banned/prohibited in ≥1 country, yellow = restricted but sold, green = no restriction) and describe ingredient-level status, not the brand. Life Extension is a commercial brand name used for identification under nominative fair use. Product data: NIH DSLD. Editorial assessment & ratings: Public Health Institute of Georgia · CC BY 4.0. Corrections:
info@accreditation.ge