1 Product identity
Ingredient risk
Contains a high-risk ingredient
Active 50+ Once Daily Multivitamin & Mineral Plus Probiotics (Digestive Support)
BrandTrader Joe's→Other Combinations Tablet or Pill 46 ingredients 1 high-risk 6 caution DSLD #26761Net contents: 60 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-10-25
2 Ingredients (46)
IngredientGroupSafety
Lemon Bioflavonoid ComplexFlavonoid (mixture)—
Nourishing Vitality Blend 4:1 Vegetable Juice ComplexBlend (Herb/Botanical)—
KaleKale—
DandelionDandelion—
Beet JuiceBeet—
Rosemary (leaf) Essential OilRosemary —
LycopeneLycopene—
Digestive SupportBlend—
ProteaseProteolytic Enzymes (Proteases)—
AmylaseAmylase—
LipaseLipase—
CellulaseCellulase—
Microcrystalline CelluloseCellulose—
Stearic AcidStearic Acid—
Clear CoatingCoating—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Molybdenum — Generally Safe
⚠ Very low toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Choline — Generally Safe
⚠ Fishy odor at high doses
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
NAC — Limited Evidence
⚠ GI upset
⚠ Rare bronchospasm
Spirulina — Limited Evidence
⚠ Contamination risk: microcystins, heavy metals
⚠ Autoimmune stimulation
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Betaine HCl — Limited Evidence
⚠ Heartburn, GI burning if used without protein meals
⚠ Not for those on H. pylori treatment
Lactobacillus — Limited Evidence
⚠ Rare sepsis if immunocompromised
⚠ Gas initially
Sodium — Limited Evidence
⚠ Hypertension
⚠ Fluid retention
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID26761
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-10-25
6 More from Trader Joe's
View Trader Joe's Safety Scorecard → 27 products
Acidophilus & Probiotic ComplexAlpha Lipoic AcidB-6/Folic Acid/B-12B-ComplexBiotin 5,000 mcgCalcium Citrate with Vitamin D37 Cite this page
Vancouver
Pkhakadze G. Active 50+ Once Daily Multivitamin & Mineral Plus Probiotics (Digestive Support) — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 28]. Available from: https://supplement.ge/products/active-50-once-daily-multivitamin-mineral-plus-probiotics-digestive-support-26761/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG