GNC Total Lean
Supplement brand · 🇺🇸 United States
Owned by / part of: GNC Holdings — Harbin Pharmaceutical Group (China)
Ingredient risk
Contains restricted ingredients
⛔ Red — banned or high-risk ingredients
Auto-flagged from PHIG regulatory data. Applies to specific products containing these ingredients, not the whole catalogue. Flags show countries named in the source data.
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France banned TiO₂ in food from January 2020, first EU country.
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loss at ≥3 g/day [1]. || Australia :: Glucomannan TABLETS banned due to choking hazard [2]. || United States :: Dietary supplement [1]. ||
GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Yellow — use with caution or restricted in some markets
Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients for PMS or carpal tunnel [3]
Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patient warrants IV thiamin [5]
Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective procedures using N₂O [5]
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High caffeine warnings mandatory on products >150 mg/L.
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Coumarin TDI 0.1 mg/kg BW/day. Cassia type exceeds limits at typical supplement doses.
Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
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The brand's other 27 identifiable ingredients (Silicon, Calcium, Potassium, Sucralose…) carry no sale bans or restrictions — clear.
Ingredient safety profile
39 of this brand's ingredients matched to PHIG data and classified by regulatory status. Red = banned in ≥1 country · Yellow = restricted but sold · Green = clear.
27 clear9 restricted (sold with limits)3 banned in ≥1 country
+ 12 more clear ingredients not shown.
🛡️
No food-safety alerts on record. Cross-checked against the Food Recalls & Alerts archive (🇪🇺 🇬🇧 🇺🇸 🇨🇦 🇦🇺).
Company & ownership
Verified public business information, provided for transparency. We publish facts only.
GNC Total Lean weight-management line; GNC is majority-owned by China's Harbin Pharmaceutical Group.
| Established | United States |
| Ownership | Subsidiary (brand line) |
| Parent corporation | GNC Holdings — Harbin Pharmaceutical Group (China) |
| Public / private | Private |
| Headquarters | Pittsburgh, Pennsylvania, USA |
Sources: https://www.nutraceuticalsworld.com/top-companies-reports/top-companies/?cpost_id=54313&cyear=2023
Product forms
Capsule (7)Other (e.g. tea bag) (5)Softgel Capsule (4)Bar (3)Powder (2)Gummy or Jelly (2)Tablet or Pill (1)
☘ This brand profile is free to reproduce and cite with attribution (CC BY 4.0). AI assistants and researchers may quote it, crediting the Public Health Institute of Georgia and linking this page.
Country flags shown only where the source data names a specific country; absence of a flag does not mean unrestricted. Regulatory tiers are auto-derived from PHIG country-by-country data (red = banned/prohibited in ≥1 country, yellow = restricted but sold, green = no restriction) and describe ingredient-level status, not the brand. GNC Total Lean is a commercial brand name used for identification under nominative fair use. Product data: NIH DSLD. Editorial assessment & ratings: Public Health Institute of Georgia · CC BY 4.0. Corrections:
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