1 Product identity
Ingredient risk
4 ingredients to use with caution
OsteoActiv
BrandDaVinci Laboratories Of Vermont→Other Combinations Capsule 18 ingredients 4 caution DSLD #23394Net contents: 150 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-09-25
2 Ingredients (18)
IngredientGroupSafety
IpriflavoneIpriflavone—
Equisetum arvenseHorsetail—
GelatinGelatin—
Rice FlourRice—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin K — Conditionally Safe
⚠ Critical interaction with warfarin
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Chondroitin — Limited Evidence
⚠ May enhance anticoagulants
Resveratrol — Conditionally Safe
⚠ Estrogenic activity
⚠ CYP enzyme inhibition
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID23394
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-09-25
6 More from DaVinci Laboratories Of Vermont
Alpha Lipoic Acid 100 mgBeauty & BrainsBilberryBromelainCalcium Citrate PlusCartilage+7 Cite this page
Vancouver
Pkhakadze G. OsteoActiv — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 17]. Available from: https://supplement.ge/products/osteoactiv-23394/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG