1 Product identity
Ingredient risk
Contains a high-risk ingredient
Men's Nutrients
BrandPure Encapsulations→Other Combinations Capsule 46 ingredients 1 high-risk 7 caution DSLD #277773Net contents: 180 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2023-01-23
2 Ingredients (46)
IngredientGroupSafety
Proprietary Mixed Carotenoid BlendProprietary Blend—
LycopeneLycopene—
ZeaxanthinZeaxanthin—
Alpha Lipoic AcidAlpha Lipoic Acid—
MacularSynergy ComplexBlend—
ProstaProtect PlusBlend—
Pygeum (Pygeum africanum) extractPygeum—
Green TeaGreen Tea—
Cardio Polyphenol ComplexBlend—
Red Wine Grape (Vitis vinifera) concentrateGrape —
Grape (Vitis vinifera) extractGrape —
Pomegranate (Punica granatum) extractPomegranate—
EnduraBoost BlendBlend—
Vegetarian Capsulecapsule—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Maca 🇺🇸 🇰🇷 🇪🇺 — ood. Dietary supplement [1]. || European Union :: Novel food ingredient [1]. || South Korea :: Dietary supplement. || Ma
3 Safety cross-reference
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Vitamin K — Limited Evidence
⚠ Critical interaction with warfarin
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Limited Evidence
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Limited Evidence
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
5-MTHF — Limited Evidence
⚠ May mask B12 deficiency like folic acid
⚠ Better tolerated than folic acid in MTHFR variants
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Choline — Generally Safe
⚠ Fishy odor at high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Chromium — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Rare renal/hepatic toxicity
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Vanadium — Limited Evidence
⚠ GI toxicity: nausea, vomiting, diarrhea
⚠ Green tongue
Lutein — Generally Safe
⚠ Harmless skin yellowing at very high doses
Inositol — High risk
⚠ GI disturbance at high doses (>12 g)
⚠ May lower blood glucose
Saw Palmetto — Generally Safe
⚠ Anti-androgenic
⚠ May affect PSA
Maca — Use with Caution
⚠ Goitrogenic
⚠ Hormonal effects
Astragalus — Generally Safe
⚠ GI upset
⚠ Rare bronchospasm
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID277773
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2023-01-23
6 More from Pure Encapsulations
View Pure Encapsulations Safety Scorecard → 126 products
7-Keto DHEAAdenosyl/Hydroxy B12 LiquidAdrenalAlpha Lipoic Acid 600 mgAlpha Lipoic Acid with GlucoPhenolAlpha-GPC7 Cite this page
Vancouver
Pkhakadze G. Men's Nutrients — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Oct 19]. Available from: https://supplement.ge/products/mens-nutrients-277773/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG