SAFE

Saw Palmetto

saw-palmetto
Possibly Safe V1 Verified
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Upper Safe Limit
For men only
PubMed Studies
47
PubChem CID
About

Fatty acids inhibit 5-alpha reductase and alpha-1 adrenergic receptors; anti-androgenic and anti-inflammatory

How it works (mechanism of action)

Used for benign prostatic hyperplasia (BPH) symptoms. Widely used in French pharmacies. Moderate evidence for urinary symptoms.

📊 Effectiveness
BPH symptoms
Evidence Grade B · 28 studies · n=4,800
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safe320mg/day
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

💊 Drug Interactions (3)
🟡 Warfarin
Moderate
Anticoagulants
Management: Avoid with anticoagulants. Stop 2 weeks before surgery.
🟡 Aspirin / Clopidogrel
Moderate
Antiplatelet drugs
Management: Avoid combination before surgery.
🟡 Anticoagulants
Moderate
Anticoagulants
Management: Monitor bleeding parameters. Discontinue 2 weeks before surgery.
🏷️ Other Names
Serenoa repens Saw palmetto extract Sabal serrulata
Updated: 2026-04-11
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