1 Product identity

Ingredient risk

Contains a high-risk ingredient

Mega Antioxidant

Name: Mega Antioxidant
Brand: USANA

BrandUSANA→Other Combinations Tablet or Pill 40 ingredients 1 high-risk 5 caution DSLD #26916

Net contents: 112 Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-11-25

2 Ingredients (40)

IngredientGroupSafety

Vitamin AVitamin AConditionally Safe

Vitamin CVitamin CGenerally Safe

Vitamin D3Vitamin DUse with Caution

Vitamin EVitamin EConditionally Safe

Vitamin B1ThiaminUse with Caution

Vitamin B2RiboflavinGenerally Safe

NiacinNiacinConditionally Safe

Vitamin B6Vitamin B6Use with Caution

FolateFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

BiotinBiotinGenerally Safe

Pantothenic AcidPantothenic Acid (Vitamin B5)—

VITAMIN KVitamin K (unspecified)—

OLIVOL(R)Olive —

Mixed Natural TocopherolsVitamin E (mixed tocopherols)—

Bioflavonoid ComplexFlavonoid (mixture)—

RutinRutin—

QUERCETINQuercetinConditionally Safe

HesperidinHesperidin—

GREEN TEA EXTRACTGreen Tea—

Pomegranate extractPomegranate—

Cinnamon extractCinnamonUse with Caution

BILBERRY EXTRACTbilberry Generally Safe

InositolInositolHigh risk

Choline BitartrateCholineGenerally Safe

N-ACETYL L-CYSTEINEN-Acetyl Cysteine—

COENZYME Q10Coenzyme Q-10—

Turmeric extractTurmericConditionally Safe

LuteinLuteinGenerally Safe

LycopeneLycopene—

Microcrystalline CelluloseCellulose—

pregelatinized StarchPregelatinized starch—

Croscarmellose SodiumCroscarmellose Sodium—

Ascorbyl PalmitateVitamin CGenerally Safe

Alpha-Lipoic AcidAlpha Lipoic Acid—

DextrinDextrin—

Silicon DioxideSiliconGenerally Safe

DextroseGlucose—

Soy Lecithinlecithin—

Sodium CitrateSodium Citrate—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Inositol — GDM prevention — 4 g/day from first trimester in high-risk women [2]

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Cinnamon 🇪🇺 — Coumarin TDI 0.1 mg/kg BW/day. Cassia type exceeds limits at typical supplement doses.

3 Safety cross-reference

Vitamin A — Conditionally Safe

⚠ Teratogenic at high doses

⚠ Hepatotoxic with chronic excess

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Vitamin E — Conditionally Safe

⚠ Increased bleeding risk

⚠ All-cause mortality at >400 IU/day

Thiamin — Use with Caution

Riboflavin — Generally Safe

⚠ Harmless yellow urine

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Biotin — Generally Safe

⚠ Interferes with troponin and thyroid lab assays

Pantothenic Acid — Limited Evidence

⚠ Diarrhea at very high doses

Vitamin K — Limited Evidence

⚠ Critical interaction with warfarin

Quercetin — Conditionally Safe

⚠ Inhibits CYP3A4

⚠ Affects cyclosporine levels

Green Tea Extract — Limited Evidence

⚠ HEPATOTOXICITY >800 mg EGCG

⚠ Iron absorption inhibition

Cinnamon — Use with Caution

⚠ Cassia: high coumarin (hepatotoxic)

⚠ May lower glucose

bilberry — Generally Safe

⚠ May increase bleeding risk at high doses

⚠ May lower blood glucose

Inositol — High risk

⚠ GI disturbance at high doses (>12 g)

⚠ May lower blood glucose

Choline — Generally Safe

⚠ Fishy odor at high doses

Coenzyme Q10 — Limited Evidence

⚠ May reduce warfarin efficacy

⚠ Mild GI effects

Lutein — Generally Safe

⚠ Harmless skin yellowing at very high doses

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Alpha-Lipoic Acid — Limited Evidence

⚠ May lower blood glucose

⚠ May lower thyroid hormones

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID26916

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-11-25

6 More from USANA

View USANA Safety Scorecard → 7 products

Active Calcium BabyCare Prenatal Chelated Mineral BabyCare Prenatal Mega Antioxidant EstroPro Poly C Proflavanol C 200

7 Cite this page

Vancouver

Pkhakadze G. Mega Antioxidant — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 27]. Available from: https://supplement.ge/products/dsld-26916/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG