1 Product identity

Ingredient risk

7 ingredients to use with caution

Pro-Shake 19 Natural Vanilla Protein Powder

Name: Pro-Shake 19 Natural Vanilla Protein Powder
Brand: Douglas Laboratories

BrandDouglas Laboratories→Multi-Vitamin and Mineral (MVM) Powder 55 ingredients 7 caution DSLD #9404

Net contents: 12 oz.

Target: Adults and Children 4 years and above

DSLD entry: 2012-06-25

2 Ingredients (55)

IngredientGroupSafety

CaloriesCalories—

Calories from FatCalories—

Total CarbohydratesCarbohydrate—

ProteinProtein (unspecified)—

Vitamin AVitamin AConditionally Safe

Vitamin CVitamin CGenerally Safe

Vitamin DVitamin DUse with Caution

Vitamin EVitamin EConditionally Safe

ThiamineThiaminUse with Caution

RiboflavinRiboflavinGenerally Safe

NiacinNiacinConditionally Safe

Vitamin B6Vitamin B6Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

BiotinBiotinGenerally Safe

Pantothenic AcidVitamin B5—

CalciumCalciumConditionally Safe

IronIronUse with Caution

IodineIodineConditionally Safe

MagnesiumMagnesiumUse with Caution

ZincZincUse with Caution

CopperCopperConditionally Safe

GlycineGlycineGenerally Safe

Hydroxyprolinehydroxyproline—

Aspartic AcidAspartic Acid—

LeucineLeucine—

Glutamic AcidGlutamic Acid—

LysineLysine—

AlanineAlanine—

ArginineArginine—

SerineSerine—

ProlineProline—

ValineValine—

IsoleucineIsoleucine—

TyrosineTyrosine—

ThreonineTHREONINE—

CystineCystine—

HistidineHistidine—

MethionineMETHIONINE—

PhenylalaninePhenylalanine—

Soy Protein isolateSoy ProteinConditionally Safe

Calcium CaseinateCasein ProteinGenerally Safe

Sodium CaseinateCasein ProteinGenerally Safe

Magnesium ProteinateMagnesiumUse with Caution

KelpKelp—

LactalbuminLactalbumin—

Vitamin A—Conditionally Safe

Vitamin B-Complex——

Vitamin CVitamin CGenerally Safe

Ferrous ProteinateIronUse with Caution

Lecithinlecithin—

Dry Cider VinegarApple Cider VinegarGenerally Safe

PapainPapainConditionally Safe

FructoseFructose—

Flavored with Natural VanillaFlavor—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].

3 Safety cross-reference

Vitamin A — Conditionally Safe

⚠ Teratogenic at high doses

⚠ Hepatotoxic with chronic excess

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Vitamin E — Conditionally Safe

⚠ Increased bleeding risk

⚠ All-cause mortality at >400 IU/day

Thiamin — Use with Caution

⚠ Very low toxicity

Riboflavin — Generally Safe

⚠ Harmless yellow urine

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Biotin — Generally Safe

⚠ Interferes with troponin and thyroid lab assays

Pantothenic Acid — Limited Evidence

⚠ Diarrhea at very high doses

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Iron — Use with Caution

⚠ GI upset, constipation

⚠ Fatal toxicity in children

Iodine — Conditionally Safe

⚠ Thyroid dysfunction at excess

⚠ Kelp: variable content

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Zinc — Use with Caution

⚠ Copper deficiency at >40 mg/day

⚠ Nausea, metallic taste

Copper — Conditionally Safe

⚠ Hepatotoxicity at high doses

Glycine — Generally Safe

⚠ Well tolerated

Soy Protein — Conditionally Safe

⚠ Isoflavones: estrogenic effects debated

⚠ Thyroid function may be affected

Casein Protein — Generally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Apple Cider Vinegar — Generally Safe

⚠ Tooth enamel erosion

⚠ Esophageal burns (undiluted)

Papain — Conditionally Safe

⚠ Allergic reactions

⚠ Increased bleeding risk

4 Label claims

• All Other

5 Data source

DSLD ID9404

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2012-06-25

6 More from Douglas Laboratories

View Douglas Laboratories Safety Scorecard → 788 products

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7 Cite this page

Vancouver

Pkhakadze G. Pro-Shake 19 Natural Vanilla Protein Powder — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 24]. Available from: https://supplement.ge/products/pro-shake-19-natural-vanilla-protein-powder-9404/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG