1 Product identity
Ingredient risk
Contains a high-risk ingredient
P.M.S.-Pack
BrandWonder Laboratories→Botanical with Nutrients Other (e.g. tea bag) 40 ingredients 1 high-risk 6 caution DSLD #315234Net contents: 30 Pack(s)
Target: Adults and Children 4 years and above
DSLD entry: 2024-09-25
2 Ingredients (40)
IngredientGroupSafety
BetaineBetaine—
BioperineBlack Pepper—
Liver, PowderLiver—
Horse Chestnut Seed ExtractHorse Chestnut—
ChasteberryChastetree—
MaltodextrinMaltodextrin—
CelluloseCellulose—
GelatinGelatin—
Stearic AcidStearic Acid—
Bone MarrowBone marrow—
VanillinVanillin—
Soybean OilSoybean Oil—
GlycerinGlycerol—
Water, PurifiedWater—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Potassium — Conditionally Safe
⚠ Hyperkalemia risk
⚠ Dangerous with ACE inhibitors
Valerian — Conditionally Safe
⚠ Drowsiness
⚠ Additive with sedatives/alcohol
Black Cohosh — High risk
⚠ HEPATOTOXICITY (rare but serious)
⚠ Limit to 6 months
Passionflower — Generally Safe
⚠ Drowsiness
⚠ Uterine stimulant
Wild Yam — Conditionally Safe
⚠ Does NOT convert to progesterone in body despite marketing claims
⚠ Estrogenic effects
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Sodium — Limited Evidence
⚠ Hypertension
⚠ Fluid retention
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID315234
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2024-09-25
6 More from Wonder Laboratories
View Wonder Laboratories Safety Scorecard → 73 products
3X Triple Strength Cranberry Concentrate5-HTP 100Acerola Vitamin C 250 mg Chewable Natural Orange FlavorAcetyl L-Carnitine 500 mgAnti-Stress + B-ComplexB-6 100 mg7 Cite this page
Vancouver
Pkhakadze G. P.M.S.-Pack — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/p-m-s-pack-315234/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG