1 Product identity

Ingredient risk

Contains restricted ingredients

Complete Cardio Heart & Cholesterol Health

Name: Complete Cardio Heart & Cholesterol Health
Brand: Irwin Naturals

BrandIrwin Naturals→Other Combinations Softgel Capsule 24 ingredients 1 banned 3 caution DSLD #44743

Net contents: 84 Liquid Softgel(s)

Target: Adults and Children 4 years and above

DSLD entry: 2015-04-24

2 Ingredients (24)

IngredientGroupSafety

Vitamin B6Vitamin B6Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

Plant Sterol EstersPhytosterol (mixed)—

Fish OilFish OilGenerally Safe

Magnesium CitrateMagnesiumUse with Caution

Hawthorn (Crataegus pinnatifida) extractHawthornConditionally Safe

Pomegranate extractPomegranate—

L-CarnitineL-CarnitineGenerally Safe

Potassium CitratePotassiumConditionally Safe

CoQ10Coenzyme Q-10—

Ginger extractGinger —

PolicosanolPolicosanol—

BioPerine ComplexProprietary Blend—

Bioperine Black Pepper extractBlack Pepper—

GelatinGelatin—

purified WaterWater—

Soy Lecithinlecithin—

GlycerinGlycerol—

BeeswaxBeeswax—

Silicon DioxideSiliconGenerally Safe

Titanium DioxideTitanium DioxideBanned in ≥1 country

Sodium Copper ChlorophyllinChlorophyllin—

TurmericTurmericConditionally Safe

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ Contains an ingredient banned in ≥1 country

Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.

⚠️ Use with caution — restricted in some markets

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Hawthorn — Conditionally Safe

⚠ Additive with digoxin

⚠ Hypotension

L-Carnitine — Generally Safe

⚠ Fishy body odor

⚠ TMAO concern

Potassium — Conditionally Safe

⚠ Hyperkalemia risk

⚠ Dangerous with ACE inhibitors

Ginger Extract — Limited Evidence

⚠ May increase bleeding risk at high doses

⚠ Heartburn

Silicon — Generally Safe

⚠ Very low toxicity

Titanium Dioxide — Banned in ≥1 country

⚠ EFSA: can no longer be considered safe as food additive (2021)

⚠ Genotoxicity concern (nanoparticles)

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID44743

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2015-04-24

6 More from Irwin Naturals

View Irwin Naturals Safety Scorecard → 24 products

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7 Cite this page

Vancouver

Pkhakadze G. Complete Cardio Heart & Cholesterol Health — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 30]. Available from: https://supplement.ge/products/complete-cardio-heart-cholesterol-health-44743/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG