1 Product identity
Ingredient risk
3 ingredients to use with caution
ArthroSoothe Supreme
BrandDesigns for Health→Other Combinations Capsule 20 ingredients 3 caution DSLD #23511Net contents: 120 Vegetarian Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-07-25
2 Ingredients (20)
IngredientGroupSafety
N-Acetyl-CysteineN-Acetyl Cysteine—
Cyplexinol(TM) PROProprietary Blend (non-nutrient/non-botanical)—
GlycoMarine(TM)New Zealand green-lipped mussel—
from 20 mg Polygonum cuspidatumHu Zhang—
Microcrystalline CelluloseCellulose—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Collagen Peptides 🇯🇵 — d health claims. Classified as a food supplement (novel food category in some jurisdictions) [2]. || Japan (MHLW) :: Col
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Glucosamine — Limited Evidence
⚠ Shellfish allergy
⚠ May affect glucose
Methylsulfonylmethane — Generally Safe
⚠ GI effects
⚠ Headache
Boswellia — Generally Safe
⚠ GI discomfort
⚠ May enhance anticoagulants
Cetyl Myristoleate — Conditionally Safe
⚠ Limited human data
⚠ GI effects
Hyaluronic acid — Generally Safe
⚠ Generally well tolerated
⚠ Theoretical concern in active cancer (promotes angiogenesis)
Resveratrol — Conditionally Safe
⚠ Estrogenic activity
⚠ CYP enzyme inhibition
Collagen Peptides — Use with Caution
Magnesium — Use with Caution
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
5 Data source
DSLD ID23511
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-07-25
6 More from Designs for Health
View Designs for Health Safety Scorecard → 261 products
5-HTP Supreme5-HTP Synergy7-KetoAcetyl L-CarnitineAcnutrolAdrenal Complex7 Cite this page
Vancouver
Pkhakadze G. ArthroSoothe Supreme — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 25]. Available from: https://supplement.ge/products/arthrosoothe-supreme-23511/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG