1 Product identity
Ingredient risk
1 ingredient to use with caution

5-HTP Synergy

BrandDesigns for HealthOther Combinations Capsule 5 ingredients 1 caution DSLD #22647
Net contents: 90 Vegetarian Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-10-25
2 Ingredients (5)
IngredientGroupSafety
Vitamin B-6Vitamin B6 (pridoxal 5-phosphate)Use with Caution
5-HTP5-HTPLimited Evidence
Microcrystalline CelluloseCellulose
Rice FlourRice
L-LeucineLeucine
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
3 Safety cross-reference
Vitamin B6 — Use with Caution
5-HTP — Limited Evidence
⚠ SEROTONIN SYNDROME with SSRIs — SERIOUS
⚠ GI disturbance
L-Leucine — Limited Evidence
⚠ May worsen pellagra
⚠ High doses may impair glucose metabolism
4 Label claims
• All Other
5 Data source
DSLD ID22647
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-10-25
6 More from Designs for Health
View Designs for Health Safety Scorecard → 261 products
5-HTP Supreme7-KetoAcetyl L-CarnitineAcnutrolAdrenal ComplexAdrenal Complex
7 Cite this page
Vancouver
Pkhakadze G. 5-HTP Synergy — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 17]. Available from: https://supplement.ge/products/5-htp-synergy-22647/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG