1 Product identity
Ingredient risk
Contains restricted ingredients
Regular Strength Estroblend
BrandEquate→Botanical with Nutrients Unknown 27 ingredients 1 banned 1 high-risk 4 caution DSLD #12200Net contents: 30 Caplet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2012-08-24
2 Ingredients (27)
IngredientGroupSafety
Proprietary Herbal Calming BlendProprietary Blend (Herb/Botanical)—
Isoflavonesisoflavone (unspecified)—
Microcrystalline CelluloseCellulose—
AcaciaAcacia—
DextrinDextrin—
HypromelloseHypromellose—
Stearic AcidStearic Acid—
Polyethylene GlycolPolyethylene glycol—
CaramelColor—
DextroseGlucose—
Lecithinlecithin—
Natural flavorFlavor—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]
⛔ Contains an ingredient banned in ≥1 country
Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
3 Safety cross-reference
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Black Cohosh — High risk
⚠ HEPATOTOXICITY (rare but serious)
⚠ Limit to 6 months
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
Sodium — Limited Evidence
⚠ Hypertension
⚠ Fluid retention
Titanium Dioxide — Banned in ≥1 country
⚠ EFSA: can no longer be considered safe as food additive (2021)
⚠ Genotoxicity concern (nanoparticles)
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID12200
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2012-08-24
6 More from Equate
View Equate Safety Scorecard → 36 products
1,000 mg Vitamin C OrangeAdvanced Triple Strength Glucosamine ChondroitinCalcium 600+D3Calcium Citrate+DCalcium Citrate+D3Children's Multivitamin Complete7 Cite this page
Vancouver
Pkhakadze G. Regular Strength Estroblend — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 30]. Available from: https://supplement.ge/products/regular-strength-estroblend-12200/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG