1 Product identity
Ingredient risk
2 ingredients to use with caution
Ester-C Plus Immune Complex
BrandSolgar→Botanical with Nutrients Softgel Capsule 16 ingredients 2 caution DSLD #264152Net contents: 90 Softgel(s)
Target: Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
DSLD entry: 2022-06-16
Brand marketing claims reviewed — Claims: quality superlatives. 3 claims assessed against named sources. See Solgar claim review →
2 Ingredients (16)
IngredientGroupSafety
Caloriesother—
Total Fatfat—
Total Carbohydratessugar—
Vitamin B6Pyridoxine Hydrochloride—
Vitamin B12Cyanocobalamin—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin A — Limited Evidence
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Vitamin C — Limited Evidence
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Limited Evidence
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Folate — Limited Evidence
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Biotin — Limited Evidence
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Elderberry — Limited Evidence
⚠ Raw berries: cyanogenic glycosides
⚠ Cytokine storm concern
NAC — Limited Evidence
⚠ GI upset
⚠ Rare bronchospasm
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID264152
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2022-06-16
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Vancouver
Pkhakadze G. Ester-C Plus Immune Complex — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/ester-c-plus-immune-complex-264152/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG