1 Product identity

Ingredient risk

5 ingredients to use with caution

NO2 Red Extreme

Name: NO2 Red Extreme
Brand: MRI

BrandMRI→Other Combinations Other (e.g. tea bag) 40 ingredients 5 caution DSLD #28794

Net contents: 150 Caplet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-12-24

2 Ingredients (40)

IngredientGroupSafety

Vitamin AVitamin AConditionally Safe

Vitamin CVitamin CGenerally Safe

Vitamin D3Vitamin DUse with Caution

Vitamin KVitamin K (unspecified)—

Vitamin B3NiacinConditionally Safe

Vitamin B6Vitamin B6Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

CalciumCalciumConditionally Safe

MagnesiumMagnesiumUse with Caution

ZincZincUse with Caution

MRI NO2 Proprietary BlendProprietary Blend (Combination)—

Advanced 5x NO BoosterBlend—

L-ArginineArginine—

L-Arginine Alpha-KetoglutarateArginine Alpha Ketoglutarate—

L-Arginine HydrochlorideArginine—

Arginine KetoisocaproateArginine alpha-ketoisocaproate—

L-Arginine PyroglutamateArginine pyroglutamate—

ACTINOSTBD—

MyoCarn Power ComplexBlend (Combination)—

Citrulline MalateCitrulline malateGenerally Safe

L-GlycineGlycineGenerally Safe

L-GlutamineGlutamineConditionally Safe

N-Acetyl-L-Carnitine HClAcetyl L-Carnitine—

CarnoSynBeta-AlanineGenerally Safe

L-HistidineHistidine—

CelluloseCellulose—

Stearic AcidStearic Acid—

Cellulose GumCellulose—

CrospovidoneCrospovidone—

Hydroxypropyl MethylcelluloseHypromellose—

Magnesium StearateMagnesium stearateUse with Caution

Silicon DioxideSiliconGenerally Safe

PolyvinylpyrrolidonePovidone—

CarboxypolymethyleneCarboxypolymethylene—

TriacetinTriacetin—

Peppermint flavorFlavor—

FD&C Red #40Color—

TalcMagnesium SilicateUse with Caution

Carnauba WaxCarnauba wax—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].

3 Safety cross-reference

Vitamin A — Conditionally Safe

⚠ Teratogenic at high doses

⚠ Hepatotoxic with chronic excess

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Vitamin K — Limited Evidence

⚠ Critical interaction with warfarin

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Zinc — Use with Caution

⚠ Copper deficiency at >40 mg/day

⚠ Nausea, metallic taste

L-Arginine — Limited Evidence

⚠ Hypotension

⚠ May worsen herpes outbreaks

Chloride — Limited Evidence

⚠ Co-ingested with sodium

Citrulline malate — Generally Safe

⚠ GI discomfort at high doses

⚠ May lower blood pressure

Glycine — Generally Safe

⚠ Well tolerated

L-Glutamine — Conditionally Safe

⚠ Hepatic encephalopathy risk

⚠ May elevate ammonia

L-Carnitine — Limited Evidence

⚠ Fishy body odor

⚠ TMAO concern

Beta-Alanine — Generally Safe

⚠ Tingling (paraesthesia) — harmless

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• Nutrient

• All Other

• Structure/Function

5 Data source

DSLD ID28794

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-12-24

6 More from MRI

View MRI Safety Scorecard → 19 products

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7 Cite this page

Vancouver

Pkhakadze G. NO2 Red Extreme — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 28]. Available from: https://supplement.ge/products/dsld-28794/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG