1 Product identity

Ingredient risk

5 ingredients to use with caution

Cleanse & Lean Advanced

Name: Cleanse & Lean Advanced
Brand: MM Sports Nutrition

BrandMM Sports Nutrition→Other Combinations Capsule 25 ingredients 5 caution DSLD #37318

Net contents: 60 Capsule(s)

Target: Adults and Children 4 years and above

DSLD entry: 2014-10-10

2 Ingredients (25)

IngredientGroupSafety

NiacinNiacinConditionally Safe

Vitamin B6Vitamin B6Use with Caution

Folic AcidFolateConditionally Safe

Vitamin B12Vitamin B12Use with Caution

Pantothenic AcidPantothenic AcidGenerally Safe

PotassiumPotassiumConditionally Safe

Appetite and Thermogenic ComplexBlend—

Slimaluma(TM) extractCaralluma—

CaffeineCaffeineUse with Caution

Green Tea extractGreen Tea—

African Mango (Irvingia gabonensis) seed extractIrvingia gabonensis—

Water Loss Support ComplexBlend (Herb/Botanical)—

Uva Ursi leaf extractUva Ursi—

Dandelion leaf extractDandelion—

Intestinal Cleanse ComplexBlend (Herb/Botanical)—

Cascara sagrada bark powder and standardized extractCascara SagradaUse with Caution

Senna leaf extractAlexandrian senna—

Fennel seed powderFennel —

Horsetail herb extractHorsetail—

Psyllium husk powderPsyllium fiber—

Slippery Elm bark powderSlippery ElmGenerally Safe

Aloe vera leaf powderAloe—

Rice powderRice—

Magnesium StearateMagnesium stearateUse with Caution

GelatinGelatin—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…

Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…

Caffeine (Anhydrous) 🇬🇧 🇪🇺 🇦🇺 — High caffeine warnings mandatory on products >150 mg/L.

Cascara Sagrada 🇪🇺 — Hydroxyanthracene derivatives under assessment.

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Niacin — Conditionally Safe

⚠ Flushing at >50 mg

⚠ Hepatotoxicity at high doses

Vitamin B6 — Use with Caution

Folate — Conditionally Safe

⚠ May mask B12 deficiency

⚠ Colorectal cancer risk debated

Vitamin B12 — Use with Caution

Pantothenic Acid — Generally Safe

⚠ Diarrhea at very high doses

Potassium — Conditionally Safe

⚠ Hyperkalemia risk

⚠ Dangerous with ACE inhibitors

Caffeine (Anhydrous) — Use with Caution

Green Tea Extract — Limited Evidence

⚠ HEPATOTOXICITY >800 mg EGCG

⚠ Iron absorption inhibition

Cascara Sagrada — Use with Caution

⚠ Stimulant laxative — same chronic abuse risk as senna

⚠ Electrolyte imbalance

Psyllium Husk — Limited Evidence

⚠ Choking risk without water

⚠ May reduce med absorption (take 2h apart)

Slippery Elm — Generally Safe

⚠ May slow medication absorption — separate 2h

⚠ GI coating effect

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID37318

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2014-10-10

6 More from MM Sports Nutrition

View MM Sports Nutrition Safety Scorecard → 120 products

2TX ADRX Amino Max Big Max Rich Chocolate Carbo Max Unflavored Cleans & Lean Defining Agent

7 Cite this page

Vancouver

Pkhakadze G. Cleanse & Lean Advanced — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/cleanse-lean-advanced-37318/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG