1 Product identity
Ingredient risk
Contains restricted ingredients
Bone & Joint Health Formula
BrandGNC Preventive Nutrition→Botanical with Nutrients Other (e.g. tea bag) 14 ingredients 1 banned 3 caution DSLD #27311Net contents: 90 Caplet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-11-25
2 Ingredients (14)
IngredientGroupSafety
Cutch Tree wood and bark extract, Chinese Skullcap root extractBlend (Herb/Botanical)—
Cutch Tree wood and bark extractCatechu—
Chinese Skullcap Root ExtractBaikal Skullcap —
MBPTBD—
CelluloseCellulose—
Vegetable AcetoglyceridesGlycerides—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ Contains an ingredient banned in ≥1 country
Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin K — Limited Evidence
⚠ Critical interaction with warfarin
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Titanium Dioxide — Banned in ≥1 country
⚠ EFSA: can no longer be considered safe as food additive (2021)
⚠ Genotoxicity concern (nanoparticles)
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID27311
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-11-25
6 More from GNC Preventive Nutrition
View GNC Preventive Nutrition Safety Scorecard → 26 products
Astaxanthin 4 mgBlood Circulation - PM PacketBone & Joint Health FormulaCardioAidCleansing Fiber SachetComfort Support7 Cite this page
Vancouver
Pkhakadze G. Bone & Joint Health Formula — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 02]. Available from: https://supplement.ge/products/bone-joint-health-formula-27311/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG