1 Product identity

Ingredient risk

1 ingredient to use with caution

Betaine HCl with Pepsin

Name: Betaine HCl with Pepsin
Brand: The Vitamin Shoppe

BrandThe Vitamin Shoppe→Non-Nutrient/Non-Botanical Tablet or Pill 13 ingredients 1 caution DSLD #55398

Net contents: 100 Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2016-02-23

2 Ingredients (13)

IngredientGroupSafety

Betaine HClBetaine Hydrochloride—

PepsinPepsin—

Microcrystalline CelluloseCellulose—

Croscarmellose SodiumCroscarmellose Sodium—

Stearic AcidStearic Acid—

LactoseLactose—

Magnesium StearateMagnesiumUse with Caution

Silicon DioxideSiliconGenerally Safe

MaltodextrinMaltodextrin—

BromelainBromelainConditionally Safe

PapainPapainConditionally Safe

clear Pharmaceutical GlazeCoating—

Peppermint OilPeppermint—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Betaine HCl — Limited Evidence

⚠ Heartburn, GI burning if used without protein meals

⚠ Not for those on H. pylori treatment

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Silicon — Generally Safe

⚠ Very low toxicity

Bromelain — Conditionally Safe

⚠ Increased bleeding risk

⚠ GI upset

Papain — Conditionally Safe

⚠ Allergic reactions

⚠ Increased bleeding risk

GLA — Limited Evidence

⚠ May lower seizure threshold

⚠ Borage oil: hepatotoxic unless PA-free

Peppermint Oil — Limited Evidence

⚠ GERD worsening

⚠ Not for infants (menthol)

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID55398

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2016-02-23

6 More from The Vitamin Shoppe

View The Vitamin Shoppe Safety Scorecard → 461 products

7-Keto 25 mg A & D Acetyl-L-Carnitine 500 mg Acetyl-L-Carnitine 500 mg Acetyl-L-Carnitine 500 mg Acetyl-L-Carnitine 500 mg

7 Cite this page

Vancouver

Pkhakadze G. Betaine HCl with Pepsin — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 28]. Available from: https://supplement.ge/products/betaine-hcl-with-pepsin-55398/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG