1 Product identity
Ingredient risk
7 ingredients to use with caution
ADDtend
BrandDouglas Laboratories→Other Combinations Capsule 32 ingredients 7 caution DSLD #10334Net contents: 120 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2012-06-25
2 Ingredients (32)
IngredientGroupSafety
DHADHA (Docosahexaenoic Acid)—
Soy Lecithinlecithin—
Lipoic AcidAlpha Lipoic Acid—
KelpKelp—
PantethinePantethine—
ProteaseProteolytic Enzymes (Proteases)—
Aloe Vera ConcentrateAloe—
AcidophilusLactobacillus acidophilus—
BifidusBifidobacterium (unspecified)—
Proprietary Blend——
GelatinGelatin—
CelluloseCellulose—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Royal Jelly 🇺🇸 🇪🇺 — Union :: Available as food supplement. Subject to novel food regulation in some contexts [1]. || United States (FDA) ::
3 Safety cross-reference
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Phosphorus — Generally Safe
⚠ Excess impairs calcium absorption
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Copper — Conditionally Safe
⚠ Hepatotoxicity at high doses
Phosphatidylserine — Generally Safe
⚠ May enhance anticoagulant effects
⚠ Soy allergy risk (soy-derived)
Royal Jelly — Use with Caution
⚠ ANAPHYLAXIS risk — especially in atopic individuals
⚠ Asthma exacerbation
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
5 Data source
DSLD ID10334
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2012-06-25
6 More from Douglas Laboratories
View Douglas Laboratories Safety Scorecard → 788 products
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Vancouver
Pkhakadze G. ADDtend — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 26]. Available from: https://supplement.ge/products/addtend-10334/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG