PubMed Studies
7
About
Goji berry contains zeaxanthin, betaine, and polysaccharides. Used for antioxidant, immune, and eye health support in TCM.
How it works (mechanism of action)
Lycium barbarum polysaccharides (LBP) bind insulin receptor on retinal ganglion cells activating PI3K/Akt neuroprotective pathway. Zeaxanthin concentrates in fovea quenching singlet oxygen. Betaine donates methyl groups in homocysteine recycling. LBP activates AMPK pathway in adipose tissue.
📊 Effectiveness
Antioxidant
Evidence Grade C · 8 studies · n=580
Eye health
Evidence Grade C · 6 studies · n=420
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Warfarin interaction (case reports). Allergy in latex-sensitive individuals.
🏷️ Other Names
Lycium barbarum