1 Product identity
Ingredient risk
2 ingredients to use with caution
Prostate Defense
BrandPrime→Botanical with Nutrients Capsule 11 ingredients 2 caution DSLD #313431Net contents: 60 Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2024-05-23
2 Ingredients (11)
IngredientGroupSafety
Plant SterolsPhystosterol (mixed)—
Pumpkin Seed ExtractPumpkin—
Dyer's Woad Root ExtractIsatis—
GelatinGelatin—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Saw Palmetto — Generally Safe
⚠ Anti-androgenic
⚠ May affect PSA
Stinging Nettle — Generally Safe
⚠ Diuretic effect
⚠ May lower blood glucose
Grape Seed Extract — Limited Evidence
⚠ Antiplatelet effect
⚠ May interact with anticoagulants
Silicon — Generally Safe
⚠ Very low toxicity
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID313431
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2024-05-23
6 More from Prime
View Prime Safety Scorecard → 5 products
Age (Age Defense Formula)Factor (Human Growth Factor Formula) For WomenHearing (Tinnitus And Ear Health Formula)Time with Horny Goat Weed7 Cite this page
Vancouver
Pkhakadze G. Prostate Defense — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/prostate-defense-313431/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG