1 Product identity
Ingredient risk
Contains a high-risk ingredient
Menopause Support With Isoflavones And Black Cohosh
BrandMartin Avenue Pharmacy→Botanical with Nutrients Tablet or Pill 20 ingredients 1 high-risk 5 caution DSLD #19585Net contents: 60 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-03-25
2 Ingredients (20)
IngredientGroupSafety
ChasteberryChastetree—
CelluloseCellulose—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ High-risk ingredient — documented serious harm
Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Vitamin B12 — Use with Caution
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Soy — Conditionally Safe
⚠ Well tolerated
Black Cohosh — High risk
⚠ HEPATOTOXICITY (rare but serious)
⚠ Limit to 6 months
Red Clover — Conditionally Safe
⚠ Estrogenic (isoflavones)
⚠ May increase bleeding risk
Dong Quai — Limited Evidence
⚠ Anticoagulant effect (coumarin)
⚠ Photosensitivity
GLA — Limited Evidence
⚠ May lower seizure threshold
⚠ Borage oil: hepatotoxic unless PA-free
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID19585
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-03-25
6 More from Martin Avenue Pharmacy
View Martin Avenue Pharmacy Safety Scorecard → 163 products
5-HTP Standardized Griffonia Extract 100 mg7-Keto DHEA 25 mgAcetyl L-Carnitine 500 mgAdrenal Health Support With Adrenal Gland ConcentrateAlfalfa 550 mgAlpha Lipoic Acid 100 mg7 Cite this page
Vancouver
Pkhakadze G. Menopause Support With Isoflavones And Black Cohosh — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/menopause-support-with-isoflavones-and-black-cohosh-19585/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG