1 Product identity

Ingredient risk

1 ingredient to use with caution

Fire and Ice

Name: Fire and Ice
Brand: Big Bold Health

BrandBig Bold Health→Other Combinations Softgel Capsule 24 ingredients 1 caution DSLD #276679

Net contents: 120 Softgel(s)

Target: Adults and Children 4 years and above

DSLD entry: 2022-11-22

2 Ingredients (24)

IngredientGroupSafety

CaloriesHeader—

Total FatFat (unspecified)—

Saturated FatSaturated fat—

Polyunsaturated FatPolyunsaturated Fat—

Monounsaturated FatMonounsaturated Fat—

CholesterolCholesterol—

Total CarbohydrateCarbohydrate (unspecified)—

ProteinProtein (unspecified)—

Vitamin AVitamin AConditionally Safe

Vitamin DVitamin DUse with Caution

Total Omega-3 Fatty AcidsOmega-3—

EPAEPA (Eicosapentaenoic Acid)—

DHADHA (Docosahexaenoic Acid)—

DPADocosapentaenoic acid—

Total Pro-Resolving MediatorsBlend—

AstaxanthinAstaxanthinGenerally Safe

Wild Alaskan Salmon OilFish OilGenerally Safe

Lemon OilLemon—

AstaxanthinAstaxanthinGenerally Safe

Sunflowersunflower—

natural Mixed TocopherolsVitamin E (mixed tocopherols)—

Fish GelatinGelatin—

GlycerinGlycerol—

Water, PurifiedWater—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]

3 Safety cross-reference

Vitamin A — Conditionally Safe

⚠ Teratogenic at high doses

⚠ Hepatotoxic with chronic excess

Vitamin D — Use with Caution

⚠ Hypercalcemia at >10,000 IU/day

⚠ Vascular calcification risk

Astaxanthin — Generally Safe

⚠ May lower blood pressure

4 Label claims

• Nutrient

• All Other

• Structure/Function

5 Data source

DSLD ID276679

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2022-11-22

6 More from Big Bold Health

View Big Bold Health Safety Scorecard → 1 products

7 Cite this page

Vancouver

Pkhakadze G. Fire and Ice — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 25]. Available from: https://supplement.ge/products/fire-and-ice-276679/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG