1 Product identity
Ingredient risk
5 ingredients to use with caution
Essential Capsules
BrandBlueprint Bryan Johnson→Other Combinations Capsule 25 ingredients 5 caution DSLD #328204Net contents: 60 Veggie Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2025-02-23
2 Ingredients (25)
IngredientGroupSafety
Broccoli Seed ExtractBroccoli—
GlucoraphaninGlucoraphanin—
FisetinFisetin—
LuteolinLuteolin—
SpermidinePolyamine (unspecified)—
LithiumLithium—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Thiamin — Wernicke encephalopathy: classic triad (confusion, ophthalmoplegia, ataxia) is present in only 16% of cases — any ONE element in an at-risk patie…
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
3 Safety cross-reference
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Thiamin — Use with Caution
⚠ Very low toxicity
Riboflavin — Generally Safe
⚠ Harmless yellow urine
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Vitamin B6 — Use with Caution
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Vitamin B12 — Use with Caution
Biotin — Generally Safe
⚠ Interferes with troponin and thyroid lab assays
Pantothenic Acid — Limited Evidence
⚠ Diarrhea at very high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Selenium — Conditionally Safe
⚠ Selenosis >400 mcg
⚠ Diabetes risk at high doses
Manganese — Conditionally Safe
⚠ Neurotoxicity with chronic excess
Coenzyme Q10 — Generally Safe
⚠ May reduce warfarin efficacy
⚠ Mild GI effects
Lactobacillus — Limited Evidence
⚠ Rare sepsis if immunocompromised
⚠ Gas initially
Boron — Conditionally Safe
⚠ Reproductive toxicity in animals
4 Label claims
• No Claim
5 Data source
DSLD ID328204
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2025-02-23
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NAC Ginger Curcumin7 Cite this page
Vancouver
Pkhakadze G. Essential Capsules — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 27]. Available from: https://supplement.ge/products/essential-capsules-328204/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG