1 Product identity

Ingredient risk

Contains restricted ingredients

ISO Lean 3

Name: ISO Lean 3
Brand: ANS

BrandANS→Other Combinations Capsule 25 ingredients 2 banned 2 caution DSLD #38841

Net contents: 60 Capsule(s)

Target: Adults and Children 4 years and above

DSLD entry: 2014-10-27

2 Ingredients (25)

IngredientGroupSafety

ISO Lean 3 Proprietary BlendProprietary Blend (Combination)—

ISO Extreme Metabolic Enhancer | Neuro Focus BlendBlend (Combination)—

Caffeine AnhydrousCaffeineUse with Caution

Citrus aurantiumBitter orangeBanned in ≥1 country

Green Tea extractGreen Tea—

R-Beta-Methyl-PEAPhenethylamine (PEA)—

MethylsynephrineMethylsynephrine—

ISOpropyl-NorsynephrineIsopropylnorsynephrine—

Yohimbine HClYohimbine—

Garcinia cambogiaGarcinia—

VinpocetineVinpocetine—

Hydro Cut BlendBlend (Herb/Botanical)—

DandelionDandelion—

Uva UrsiUva Ursi—

JuniperJuniper—

Buchu extractBuchu (unspecified)—

Thermogenic Delivery SystemBlend—

MCT oilMedium chain triglycerides (MCT)—

GelatinGelatin—

Dicalcium PhosphateCalciumConditionally Safe

Magnesium StearateMagnesium stearateUse with Caution

Titanium DioxideTitanium DioxideBanned in ≥1 country

SilicaSiliconGenerally Safe

FD&C Blue #1Color—

FD&C Red #40Color—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ Contains an ingredient banned in ≥1 country

Bitter Orange — but minimal α-1/α-2 activity (distinguishing it from the banned ephedrine) [1]. Despite widespread use in fat-burners and pre-workouts, c

Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.

⚠️ Use with caution — restricted in some markets

Caffeine (Anhydrous) 🇬🇧 🇪🇺 🇦🇺 — High caffeine warnings mandatory on products >150 mg/L.

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Caffeine (Anhydrous) — Use with Caution

Bitter Orange — Banned in ≥1 country

⚠ Cardiovascular events when combined with caffeine

⚠ Hypertension, tachycardia

Green Tea Extract — Limited Evidence

⚠ HEPATOTOXICITY >800 mg EGCG

⚠ Iron absorption inhibition

Garcinia Cambogia — Limited Evidence

⚠ HEPATOTOXICITY — multiple case reports of liver failure

⚠ Mania/psychosis reported

MCT Oil — Limited Evidence

⚠ GI distress initially

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Titanium Dioxide — Banned in ≥1 country

⚠ EFSA: can no longer be considered safe as food additive (2021)

⚠ Genotoxicity concern (nanoparticles)

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID38841

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2014-10-27

6 More from ANS

View ANS Safety Scorecard → 20 products

DAA Test 5 ISO Lean 1 ISO Lean 2 Methyl Drive Methyl Drive Methyl Drive 2.0

7 Cite this page

Vancouver

Pkhakadze G. ISO Lean 3 — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jul 29]. Available from: https://supplement.ge/products/dsld-38841/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG