1 Product identity
Ingredient risk
6 ingredients to use with caution

Fifty Plus Formula

BrandSimply SupplementsMulti-Vitamin and Mineral (MVM) Tablet or Pill 17 ingredients 6 caution DSLD #22195
Net contents: 180 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-06-25
2 Ingredients (17)
IngredientGroupSafety
Vitamin CVitamin CGenerally Safe
MagnesiumMagnesiumUse with Caution
Vitamin B3Vitamin B3 (unspecified)
Vitamin EVitamin EConditionally Safe
IronIronUse with Caution
Vitamin B6Vitamin B6Use with Caution
Vitamin B1Vitamin B1 (unspecified)
Vitamin AVitamin AConditionally Safe
ZincZincUse with Caution
Folic AcidFolateConditionally Safe
IodineIodineConditionally Safe
Vitamin D3Vitamin DUse with Caution
Vitamin B12Vitamin B12Use with Caution
Microcrystalline CelluloseCellulose
SilicaSiliconGenerally Safe
Stearic AcidStearic Acid
Magnesium StearateMagnesium stearateUse with Caution
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
Iron — Iron supplementation in iron-replete patients may increase cardiovascular and cancer risk — always document deficiency before prescribing [1].
Vitamin B6 — Sensory neuropathy from chronic high-dose B6 (>200 mg/day) — presents as numbness, ataxia. Can be irreversible. Often self-prescribed by patients…
Zinc — Chronic zinc >40 mg/day without copper causes copper deficiency: anemia, neutropenia, myeloneuropathy [1].
Vitamin D — Granulomatous diseases (sarcoidosis, TB) — unregulated extra-renal CYP27B1 can cause life-threatening hypercalcemia even at standard doses [2][21]
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
3 Safety cross-reference
Vitamin C — Generally Safe
⚠ GI distress at high doses
⚠ Kidney stones risk >1g/day
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Vitamin E — Conditionally Safe
⚠ Increased bleeding risk
⚠ All-cause mortality at >400 IU/day
Iron — Use with Caution
⚠ GI upset, constipation
⚠ Fatal toxicity in children
Vitamin B6 — Use with Caution
Vitamin A — Conditionally Safe
⚠ Teratogenic at high doses
⚠ Hepatotoxic with chronic excess
Zinc — Use with Caution
⚠ Copper deficiency at >40 mg/day
⚠ Nausea, metallic taste
Folate — Conditionally Safe
⚠ May mask B12 deficiency
⚠ Colorectal cancer risk debated
Iodine — Conditionally Safe
⚠ Thyroid dysfunction at excess
⚠ Kelp: variable content
Vitamin D — Use with Caution
⚠ Hypercalcemia at >10,000 IU/day
⚠ Vascular calcification risk
Vitamin B12 — Use with Caution
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
5 Data source
DSLD ID22195
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-06-25
6 More from Simply Supplements
View Simply Supplements Safety Scorecard → 47 products
AcidophilusAlpha Lipoic Acid 250 mgApple Cider VinegarBiotin 10,000 mcgBlack Cohosh 200 mgCalcium 400 mg & Magnesium 200 mg
7 Cite this page
Vancouver
Pkhakadze G. Fifty Plus Formula — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 30]. Available from: https://supplement.ge/products/dsld-22195/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
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