1 Product identity

Ingredient risk

1 ingredient to use with caution

Digestive Enzymes

Name: Digestive Enzymes
Brand: GPI

BrandGPI→Other Combinations Other (e.g. tea bag) 24 ingredients 1 caution DSLD #28699

Net contents: 60 Caplet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-12-24

2 Ingredients (24)

IngredientGroupSafety

AmylaseAmylase—

ProteaseProteolytic Enzymes (Proteases)—

LipaseLipase—

CellulaseCellulase—

In a base ofBlend (Combination)—

AlfalfaAlfalfa—

Betaine HClBetaine Hydrochloride—

PapainPapainConditionally Safe

BromelainBromelainConditionally Safe

ChamomileChamomile (unspecified)—

FenugreekFenugreekConditionally Safe

FennelFennel —

GingerGinger —

LactaseLactaseGenerally Safe

LicoriceLicorice —

PeppermintPeppermint—

Dicalcium PhosphateCalciumConditionally Safe

Microcrystalline CelluloseCellulose—

Stearic AcidStearic Acid—

Croscarmellose SodiumCroscarmellose Sodium—

Magnesium StearateMagnesiumUse with Caution

SilicaSiliconGenerally Safe

Calcium SilicateCalcium Silicate—

pharmaceutical glazeCoating—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Betaine HCl — Limited Evidence

⚠ Heartburn, GI burning if used without protein meals

⚠ Not for those on H. pylori treatment

Papain — Conditionally Safe

⚠ Allergic reactions

⚠ Increased bleeding risk

Bromelain — Conditionally Safe

⚠ Increased bleeding risk

⚠ GI upset

Fenugreek — Conditionally Safe

⚠ Hypoglycemia

⚠ Maple syrup odor

Lactase — Generally Safe

⚠ Very well tolerated

⚠ Fungal-derived: rare allergy

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Silicon — Generally Safe

⚠ Very low toxicity

GLA — Limited Evidence

⚠ May lower seizure threshold

⚠ Borage oil: hepatotoxic unless PA-free

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID28699

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-12-24

6 More from GPI

View GPI Safety Scorecard → 12 products

Combination 23 Honeybee Pollen 500 mg Honeybee Pollen Professional Honeybee Propolis Honeybee Propolis OC-MAX

7 Cite this page

Vancouver

Pkhakadze G. Digestive Enzymes — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 25]. Available from: https://supplement.ge/products/digestive-enzymes-28699/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG