1 Product identity

Ingredient risk

Contains restricted ingredients

C-1000

Name: C-1000
Brand: 21st Century

Brand21st Century→Vitamin Tablet or Pill 11 ingredients 1 banned 1 caution DSLD #43552

Net contents: 500 Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2015-03-25

2 Ingredients (11)

IngredientGroupSafety

Vitamin CVitamin CGenerally Safe

CelluloseCellulose—

Calcium CarbonateCalciumConditionally Safe

Stearic AcidStearic Acid—

Croscarmellose SodiumCroscarmellose Sodium—

Silicon DioxideSiliconGenerally Safe

Mag StearateMagnesium stearateUse with Caution

Polyvinyl AlcoholPolyvinyl alcohol—

Titanium DioxideTitanium DioxideBanned in ≥1 country

PEGPolyethylene glycol—

TalcMagnesium SilicateUse with Caution

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ Contains an ingredient banned in ≥1 country

Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Vitamin C — Generally Safe

⚠ GI distress at high doses

⚠ Kidney stones risk >1g/day

Calcium — Conditionally Safe

⚠ Cardiovascular risk debated >1,000 mg/day

⚠ Kidney stones

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Silicon — Generally Safe

⚠ Very low toxicity

Magnesium — Use with Caution

Titanium Dioxide — Banned in ≥1 country

⚠ EFSA: can no longer be considered safe as food additive (2021)

⚠ Genotoxicity concern (nanoparticles)

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID43552

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2015-03-25

6 More from 21st Century

View 21st Century Safety Scorecard → 179 products

600 + D3 plus Minerals 600 Calcium Supplement 600+D3 600+D3 600+D3 Acai 1000 mg

7 Cite this page

Vancouver

Pkhakadze G. C-1000 — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 24]. Available from: https://supplement.ge/products/c-1000-43552/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG