1 Product identity

Ingredient risk

Contains a high-risk ingredient

Transitions

Name: Transitions
Brand: Pure Essence

BrandPure Essence→Other Combinations Capsule 19 ingredients 1 high-risk DSLD #327538

Net contents: 120 Vegi Cap(s)

Target: Adults and Children 4 years and above

DSLD entry: 2025-03-25

2 Ingredients (19)

IngredientGroupSafety

Gamma-OryzanolGamma oryzanol—

HesperidinHesperidin—

Burdock Root ExtractBurdock —

Chaste Tree Fruit ExtractChastetree—

Hesperidin MethylchalconeHesperidin—

Kudzu Root ExtractKudzu —

Eleuthero Root ExtractEleuthero—

Motherwort extractMotherwort—

Dong Quai Root ExtractDong QuaiLimited Evidence

Black Cohosh Root ExtractBlack CohoshHigh risk

Fo-Ti Root ExtractFo-Ti—

Poria cocos extractPoria Mushroom—

Rehmannia Root ExtractRehmannia—

White Peony Root ExtractWhite Peony—

Wild YamWild YamConditionally Safe

L-LeucineLeucine—

Silicon DioxideSiliconGenerally Safe

CelluloseCellulose—

Hydroxypropyl MethylcelluloseHypromellose—

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]

3 Safety cross-reference

Dong Quai — Limited Evidence

⚠ Anticoagulant effect (coumarin)

⚠ Photosensitivity

Black Cohosh — High risk

⚠ HEPATOTOXICITY (rare but serious)

⚠ Limit to 6 months

Wild Yam — Conditionally Safe

⚠ Does NOT convert to progesterone in body despite marketing claims

⚠ Estrogenic effects

L-Leucine — Limited Evidence

⚠ May worsen pellagra

⚠ High doses may impair glucose metabolism

Silicon — Generally Safe

⚠ Very low toxicity

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID327538

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2025-03-25

6 More from Pure Essence

View Pure Essence Safety Scorecard → 7 products

AllerFree Breast-D Candex Immunin-6 ProFema ProstateEssence

7 Cite this page

Vancouver

Pkhakadze G. Transitions — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 26]. Available from: https://supplement.ge/products/transitions-327538/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG