Standardized Black Cohosh & Soy Isoflavones 100% Vegetarian

Name: Standardized Black Cohosh & Soy Isoflavones 100% Vegetarian
Brand: 21st Century

Brand21st Century→Botanical Capsule 7 ingredients 1 high-risk 1 caution DSLD #20664

Net contents: 200 Vegetarian Capsule(s)

Target: Adults and Children 4 years and above

DSLD entry: 2013-04-25

2 Ingredients (7)

IngredientGroupSafety

Black Cohosh ExtractBlack CohoshHigh risk

Soy Isoflavonesisoflavone (unspecified)—

Rice BranRice Bran—

Oat FiberOat Fiber—

Vegetable CelluloseCellulose—

Magnesium SilicateMagnesium SilicateUse with Caution

Magnesium StearateMagnesium stearateUse with Caution

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ High-risk ingredient — documented serious harm

Black Cohosh 🇺🇸 🇦🇺 🇪🇺 — Hepatotoxicity cases including liver failure — limit 6 months [1]

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

Black Cohosh — High risk

⚠ HEPATOTOXICITY (rare but serious)

⚠ Limit to 6 months

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID20664

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2013-04-25

6 More from 21st Century

View 21st Century Safety Scorecard → 179 products

600 + D3 plus Minerals 600 Calcium Supplement 600+D3 600+D3 600+D3 Acai 1000 mg

7 Cite this page

Vancouver

Pkhakadze G. Standardized Black Cohosh & Soy Isoflavones 100% Vegetarian — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Oct 18]. Available from: https://supplement.ge/products/standardized-black-cohosh-soy-isoflavones-100-vegetarian-20664/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG