1 Product identity

Ingredient risk

Contains restricted ingredients

SAM-e 200 mg

Name: SAM-e 200 mg
Brand: 365 Everyday Value

Brand365 Everyday Value→Non-Nutrient/Non-Botanical Tablet or Pill 15 ingredients 1 banned 1 caution DSLD #60793

Net contents: 30 Enteric-Coated Tablet(s)

Target: Adults and Children 4 years and above

DSLD entry: 2016-06-24

2 Ingredients (15)

IngredientGroupSafety

S-Adenosyl MethionineSAMeConditionally Safe

SAMeSAMeConditionally Safe

CelluloseCellulose—

MannitolMannitol—

Carboxymethylstarch Sodium SaltCarboxy Methyl Cellulose—

Silicon DioxideSiliconGenerally Safe

Glycerol BehenateGlyceride—

Magnesium StearateMagnesium StearateUse with Caution

Methacrylic Acid Co-PolymerPolyacrylate—

Glycerol PalmitostearateGlyceryl palmitostearate—

Medium Chain TriglyceridesMedium chain triglycerides (MCT)—

Titanium DioxideTitanium DioxideBanned in ≥1 country

TalcMagnesium SilicateUse with Caution

Triethyl Citratetriethylcitrate—

RiboflavinRiboflavinGenerally Safe

Ingredient amounts require the full DSLD label. View full label at NIH DSLD →

⛔ Contains an ingredient banned in ≥1 country

Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.

⚠️ Use with caution — restricted in some markets

Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].

3 Safety cross-reference

SAMe — Conditionally Safe

⚠ Mania in bipolar

⚠ Serotonin syndrome with SSRIs

Sodium — Limited Evidence

⚠ Hypertension

⚠ Fluid retention

Silicon — Generally Safe

⚠ Very low toxicity

Magnesium — Use with Caution

⚠ Diarrhea (especially oxide)

⚠ Accumulates in renal impairment

Titanium Dioxide — Banned in ≥1 country

⚠ EFSA: can no longer be considered safe as food additive (2021)

⚠ Genotoxicity concern (nanoparticles)

Riboflavin — Generally Safe

⚠ Harmless yellow urine

4 Label claims

• All Other

• Structure/Function

5 Data source

DSLD ID60793

Full labelView at NIH DSLD →

SourceOffice of Dietary Supplements, NIH

Market statusOn market

Entry date2016-06-24

6 More from 365 Everyday Value

View 365 Everyday Value Safety Scorecard → 11 products

Adult Multi for Men CoQ10 Plus Vitamin E Filtered Flax Oil Fish Oil 1000 mg Fish Oil 1000 mg Folic Acid 400 mcg

7 Cite this page

Vancouver

Pkhakadze G. SAM-e 200 mg — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 24]. Available from: https://supplement.ge/products/sam-e-200-mg-60793/

CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.

Analyzed by SupplementIndex

PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD

Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG