1 Product identity
Ingredient risk
1 ingredient to use with caution
Niacinamide 500 mg
Brand21st Century→Single Vitamin and Mineral Tablet or Pill 12 ingredients 1 caution DSLD #326336Net contents: 110 Tablet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2025-03-25
2 Ingredients (12)
IngredientGroupSafety
CelluloseCellulose—
Hydroxypropyl MethylcelluloseHypromellose—
Stearic AcidStearic Acid—
Gum AcaciaAcacia—
Polyethylene GlycolPolyethylene glycol—
PolysorbatePolysorbate—
Polyvinyl AlcoholPolyvinyl alcohol—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Niacin — Conditionally Safe
⚠ Flushing at >50 mg
⚠ Hepatotoxicity at high doses
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID326336
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2025-03-25
6 More from 21st Century
View 21st Century Safety Scorecard → 179 products
600 + D3 plus Minerals600 Calcium Supplement600+D3600+D3600+D3Acai 1000 mg7 Cite this page
Vancouver
Pkhakadze G. Niacinamide 500 mg — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Jun 24]. Available from: https://supplement.ge/products/niacinamide-500-mg-326336/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG