1 Product identity
Ingredient risk
Contains restricted ingredients
Methyl B-12 2500 mcg
BrandGNC→Single Vitamin and Mineral Other (e.g. tea bag) 13 ingredients 1 banned 2 caution DSLD #260268Net contents: 100 Caplet(s)
Target: Adults and Children 4 years and above
DSLD entry: 2022-02-23
2 Ingredients (13)
IngredientGroupSafety
Microcrystalline CelluloseCellulose—
Hydroxypropyl MethylcelluloseHypromellose—
Stearic AcidStearic Acid—
Polyethylene GlycolPolyethylene glycol—
Carnauba waxCarnauba wax—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⛔ Contains an ingredient banned in ≥1 country
Titanium Dioxide 🇫🇷 🇪🇺 — France banned TiO₂ in food from January 2020, first EU country.
⚠️ Use with caution — restricted in some markets
Vitamin B12 — Nitrous oxide anesthesia in subclinically B12-deficient patients can precipitate acute combined degeneration — always check B12 before elective p…
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Vitamin B12 — Use with Caution
Calcium — Conditionally Safe
⚠ Cardiovascular risk debated >1,000 mg/day
⚠ Kidney stones
Silicon — Generally Safe
⚠ Very low toxicity
Titanium Dioxide — Banned in ≥1 country
⚠ EFSA: can no longer be considered safe as food additive (2021)
⚠ Genotoxicity concern (nanoparticles)
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Sodium — Limited Evidence
⚠ Hypertension
⚠ Fluid retention
4 Label claims
• Nutrient
• All Other
• Structure/Function
5 Data source
DSLD ID260268
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2022-02-23
6 More from GNC
View GNC Safety Scorecard → 42 products
Activated Charcoal 520 mgBiotin 5000 mcgBiotin 5000 mcgBiotin 5000 mcg BerryBiotin 600 mcgCalcium 600 mg7 Cite this page
Vancouver
Pkhakadze G. Methyl B-12 2500 mcg — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Oct 22]. Available from: https://supplement.ge/products/methyl-b-12-2500-mcg-260268/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG