1 Product identity
Ingredient risk
3 ingredients to use with caution
Metapan
BrandMarco Pharma Int'l→Other Combinations Capsule 21 ingredients 3 caution DSLD #25378Net contents: 90 Veggie Capsule(s)
Target: Adults and Children 4 years and above
DSLD entry: 2013-09-25
2 Ingredients (21)
IngredientGroupSafety
Proprietary Blend {Combination}Proprietary Blend (Combination)—
Bitter Melon extractBitter Melon—
Jambolan extractJambolan—
Curcumin extractCurcumin—
White Kidney Beans extractBean—
Cayenne Pepper extractCapsicum—
CellulaseCellulase—
AcaciaAcacia—
Black Pepper extractBlack Pepper—
Banababanaba—
Alpha Lipoic AcidAlpha Lipoic Acid—
CelluloseCellulose—
Ingredient amounts require the full DSLD label. View full label at NIH DSLD →
⚠️ Use with caution — restricted in some markets
Cinnamon 🇪🇺 — Coumarin TDI 0.1 mg/kg BW/day. Cassia type exceeds limits at typical supplement doses.
Neem 🇪🇺 🇨🇦 — Neem oil as food additive restricted. Assessment incomplete.
Magnesium — Severe deficiency (<0.50 mmol/L) causes secondary hypocalcemia and hypokalemia that will not correct until magnesium is repleted first [1].
3 Safety cross-reference
Gymnema — Conditionally Safe
⚠ Hypoglycemia with diabetes meds
⚠ Temporarily suppresses sweet taste
Cinnamon — Use with Caution
⚠ Cassia: high coumarin (hepatotoxic)
⚠ May lower glucose
Fenugreek — Conditionally Safe
⚠ Hypoglycemia
⚠ Maple syrup odor
Neem — Use with Caution
⚠ Hepatotoxicity and nephrotoxicity at high doses
⚠ Anti-fertility effects (both sexes)
Green Tea Extract — Limited Evidence
⚠ HEPATOTOXICITY >800 mg EGCG
⚠ Iron absorption inhibition
Guggul — Limited Evidence
⚠ GI upset, headache
⚠ Thyroid stimulation
L-Carnitine — Generally Safe
⚠ Fishy body odor
⚠ TMAO concern
Magnesium — Use with Caution
⚠ Diarrhea (especially oxide)
⚠ Accumulates in renal impairment
Silicon — Generally Safe
⚠ Very low toxicity
4 Label claims
• All Other
• Structure/Function
5 Data source
DSLD ID25378
Full labelView at NIH DSLD →
SourceOffice of Dietary Supplements, NIH
Market statusOn market
Entry date2013-09-25
6 More from Marco Pharma Int'l
View Marco Pharma Int'l Safety Scorecard → 15 products
AccelerinBa-Co-FlorBa-Co-FlorCerebro PTCColostrumEnerdreen7 Cite this page
Vancouver
Pkhakadze G. Metapan — product analysis [Internet]. Tbilisi: Public Health Institute of Georgia; 2026 [cited 2026 Aug 24]. Available from: https://supplement.ge/products/metapan-25378/
CC BY 4.0. Product data from NIH DSLD; safety analysis by SupplementIndex.
GP
Analyzed by SupplementIndex
PHIG · Editor-in-Chief: Prof. Giorgi Pkhakadze, MD, MPH, PhD
Product data sourced from the NIH Dietary Supplement Label Database (DSLD). Safety cross-referencing by SupplementIndex. This analysis is for informational purposes only. For corrections: info@accreditation.ge.
Publisher: PHIG
Publisher: PHIG